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      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 8 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Thinking about adding PRP - any real downsides?

      in Treatment  7 upvotes 7 months ago
      The user has been using minoxidil, finasteride, dermastamping, and Nizoral for hair loss with initial success but is considering adding PRP due to slowed progress. Concerns about PRP include potential ineffectiveness and whether it could harm existing hair growth or interfere with current treatments.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 1 month ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community The temporal peak - the often forgotten part in transplants?

      in Transplants  88 upvotes 10 months ago
      Temporal peaks are crucial for a natural-looking hair transplant, but they are challenging to achieve due to the need for precise angles and appropriate hair thickness. Many users emphasize the importance of finding a skilled surgeon and using finasteride to maintain hairline stability.

      community Started tretinoin, lost a bunch of new hairs - normal?

      in Progress Pictures  35 upvotes 1 year ago
      The user experienced increased hair shedding after adding tretinoin to their regimen of finasteride, minoxidil, and dermarolling, but noticed new vellus hairs appearing. They plan to restart tretinoin more gently, as some users suggest shedding indicates treatment effectiveness, while others warn it may cause severe thinning for a minority.

      community Can topicals cause a never ending shed?

      in Treatment  2 upvotes 2 years ago
      The user reintroduced RU58841 and noticed increased shedding and visible thinning. They have also been using dutasteride and oral minoxidil for 2 years.

      community New Breezula Update ( I think)

      in Treatment  18 upvotes 6 months ago
      Breezula's phase 3 enrollment for hair loss treatment is complete, but results have not been published, causing skepticism about its progress. Some users express doubt about its future, suggesting it may be reserved for exclusive use.

      community Creating an all-in one topical. Dumb idea?

      in Treatment 3 years ago
      The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.

      community Topical Hyper-responder not responding to oral

      in Finasteride/Dutasteride  127 upvotes 1 month ago
      A user experienced significant hair loss after switching from topical to oral finasteride and minoxidil, despite initially seeing great results with the topical treatment. They are seeking advice on whether to return to topical treatments or increase their oral minoxidil dosage.

      community Who's tried these topical solutions?

      in Treatment  10 upvotes 2 years ago
      Topical melatonin, caffeine, and adenosine have shown impressive results in increasing hair density by 55% in 8 weeks, according to a Medium article.

      community The likely cost of HMI-115, when it comes out

      in Technology  12 upvotes 3 years ago
      A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

      community Failed HT or expected result? 4505 grafts, Eugenix, New Delhi.

      in Transplants  36 upvotes 1 year ago
      The hair transplant at Eugenix in New Delhi resulted in poor density and texture, with only about 2,500 grafts surviving out of 4,500. The user is considering holding the clinic accountable and exploring options like shaving, using hair fibers, or seeking another transplant.

      community A positive thought rolling into Christmas

      in Research/Science  12 upvotes 5 months ago
      The conversation is optimistic about future hair loss treatments, highlighting Veradermics, Breezula, and PP405 as promising options expected by 2027-2028. The user expresses hope that these developments will prevent future generations from experiencing the same struggles with hair loss.

      community Did anyone tried exosome therapy

      in Treatment  1 upvotes 1 year ago
      Exosome therapy for hair loss is questioned for its effectiveness and authenticity. Users express skepticism, citing manipulated photos and high costs.

      community To everyone who cant use FIN and doesnt want to use RU

      in Treatment  33 upvotes 1 year ago
      A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

      community topical fluridil/eucapil + dut to block all DHT+T from scalp?

      in Treatment  8 upvotes 4 years ago
      User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

      community 4 days after a hair transplant

      in Satire  1499 upvotes 9 months ago
      A satirical discussion about a hair transplant, with humorous comments on graft placement and clinic choice. The conversation includes references to a "Rebuild a Scalp Clinic" and jokes about using pubic hair and overharvesting.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Feels like this subreddit lately

      in Satire  244 upvotes 1 year ago
      People are discussing hair loss treatments, including finasteride, minoxidil, and dutasteride, focusing on maintenance and potential regrowth. Some users joke about unrealistic expectations, while others share experiences and advice on treatment options.

      community Has anyone tried Peptonix microneedling?

      in Product  4 upvotes 6 months ago
      The conversation discusses Peptonix microneedling, a copper peptide serum, as a potential hair loss treatment. Users compare it to finasteride and minoxidil, noting side effects and personal experiences with these treatments.

      community Why so much hate for PP405 all of a sudden?

      in Technology  48 upvotes 9 months ago
      PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.