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      community Oral Minoxidil Study of 60 AGA patients

      in Minoxidil  69 upvotes 4 years ago
      Oral minoxidil treatment increased hair density and shaft caliber in AGA patients. Side effects included hypertrichosis and lower extremity edema, with younger patients experiencing fewer side effects.

      community Groundbreaking sugar gel might be a miracle hair loss solution for men and women

      in Technology  124 upvotes 1 year ago
      A sugar gel called 2-deoxy-D-ribose (2dDR) shows potential for promoting hair regrowth by increasing blood supply to hair follicles, similar to Minoxidil, but its effectiveness in humans is unproven. It may benefit those who don't tolerate Minoxidil, but it is not a replacement for treatments like Finasteride or RU58841.

      community Creatine made all my high DHT symptoms return

      in Research/Science  80 upvotes 1 year ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community Anyone tried GHK-CU for hair loss?

      in Treatment  6 upvotes 9 months ago
      The conversation is about using GHK-Cu, a copper peptide, for hair loss treatment. Users discuss their experiences, dosages, and additional benefits like improved skin and energy.

      community Low Estradiol while on 1mg Fin, what should I do?

      in Finasteride/Dutasteride  2 upvotes 11 months ago
      A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 1 month ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Bloodwork Results. DHT and Testosterone Levels

      in Update  6 upvotes 1 year ago
      The user shared their bloodwork results showing DHT at 17 ng/dl and testosterone at 287 ng/dl, with a slight Vitamin D deficiency. They are seeking opinions on these levels and have an upcoming dermatologist appointment.

      community Malabsorption: Nutrient Testing and Supplementation

      in Treatment  2 upvotes 1 year ago
      The user is experiencing severe hair loss due to gut malabsorption and is seeking advice on nutrient testing and supplementation. They have low Vitamin D and Ferritin levels and are asking for recommendations on additional nutrients and blood tests to consider.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.
      22M Seeking Advice: Gyno, Insulin Resistance and Hair Loss Solutions

      community 22M Seeking Advice: Gyno, Insulin Resistance and Hair Loss Solutions

      in General  269 upvotes 6 months ago
      A 22-year-old is experiencing hair loss and anxiety, trying treatments like topical finasteride, rosemary oil, caffeine, microneedling, low-level laser therapy, scalp massages, ketoconazole shampoo, and various vitamins. They are concerned about potential gynecomastia and are considering using minoxidil if current treatments don't stop hair loss or promote regrowth.

      community GHK-cu/Ahk-cu mix with minoxidil

      in Treatment  2 upvotes 1 year ago
      A user is seeking advice on mixing GHK-cu/AHK-cu with minoxidil for hair loss treatment. They are asking for recommendations on the correct mixing ratios and any experiences with copper peptides.

      community Hormonal panel after 1 year of treatment - DHT levels doubled!!

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

      community Hyperbaric Oxygen Therapy (HBOT)

      in Research/Science  8 upvotes 4 years ago
      Hyperbaric Oxygen Therapy (HBOT) is discussed as a potential treatment for androgenic alopecia due to its ability to reverse hypoxia and promote angiogenesis. The conversation explores its potential benefits for hair loss, though no studies have been conducted on this application yet.

      community 23M Wierd blood test results after 7 months on finasteroid (1mg daily)

      in Finasteride/Dutasteride  5 upvotes 3 months ago
      A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

      community Finasteride/dutasteride todo mal

      in Finasteride/Dutasteride  2 upvotes 1 week ago
      The user experienced persistent acne and skin issues with dutasteride, leading them to stop its use. They switched to finasteride, which caused mild acne and potential liver concerns, prompting consideration of alternative treatments like topical finasteride and GHK-Cu.

      community Dont know what the hell is going on.

      in Chat  6 upvotes 1 year ago
      The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

      community high estrogen levels after 10month fin

      in Finasteride/Dutasteride  9 upvotes 2 years ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

      in Research/Science  133 upvotes 6 months ago
      A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.