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PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

The user treated seborrheic dermatitis by cutting sugar, improving sleep, using four different shampoos, and occasionally using steroids. Their hair is growing back thicker and new hair is appearing.

User noticed tiny black hairs on temples after using rosemary oil along with finasteride, minoxidil, and 0.5mm derma roller. They are curious if these hairs will become terminal.

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

If treatments like finasteride, minoxidil, PRP, microneedling, and exosomes fail, opinions differ on using a hair system or shaving. Some choose shaving for simplicity, while others consider hair systems despite maintenance concerns.

A user shared their positive experience using keratin hair thickening fibers to conceal a balding crown after six months on finasteride. Other users discussed various hair loss solutions, including minoxidil, dermarolling, and scalp micropigmentation.

A user reported using oral Minoxidil 3mg, oral Finasteride 1mg, topical Minoxidil, dermarolling twice a week, and taking biotin and vitamin D daily for 10 weeks. They noticed small hairs growing at the hairline after 6 weeks.

A 34-year-old male is experiencing hair loss on the sides of his head, with inflammation and itchiness, while the top remains thick. He is using topical dutasteride and keto shampoo to address the issue.

The conversation discusses hair flattening and improving hair health. It mentions using supplements to increase keratin in the hair.

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

The user experienced significant hair regrowth using minoxidil, microneedling, and estrogen, leading to a need to tie their hair back. They attribute the success to estrogen suppressing testosterone, alongside their routine of minoxidil, microneedling, and supplements.

User "mo_movic" shared 4-month progress using finasteride, minoxidil, ketoconazole, and dermaroller for hair loss. Others congratulated and discussed their own experiences, with "mo_movic" reducing finasteride dose and using ketoconazole twice a week.

Hair loss from headspin friction might be improved with minoxidil if follicles are healthy. Finasteride isn't needed, and microneedling is suggested.

Hair loss has slowed, but uneven growth and kinking persist despite using keto/nizoral shampoo and clotrimazole. Stress and anxiety might be contributing factors.

The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

The user is experiencing hair thinning and bald spots, using Nizoral, rosemary oil, fluocinolone, and receiving PRP treatments. They are considering oral minoxidil and finasteride but are hesitant due to age and financial constraints.

The user experienced significant hair improvement with minoxidil and finasteride but later faced shedding and diffused thinning after developing seborrheic dermatitis. They are seeking advice after trying treatments like ketoconazole, coal tar shampoos, fluconazole, and hydrocortisone cream.

The user is frustrated with ongoing hair loss despite using treatments like dutasteride, finasteride, and minoxidil, and is considering shaving their head. They are advised to maintain consistency with medication, consider oral minoxidil, and explore hair transplant options.

Female with PCOS experiences receding and thinning hair, wants dutasteride instead of spironolactone. Discusses desire to reduce DHT without losing libido.

The user is experiencing hair loss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.

The user is frustrated with hair loss despite using minoxidil, topical finasteride, and topical dutasteride, and is considering other options like oral treatments, SMP, or hair systems. They feel demoralized and are struggling with self-esteem and social interactions due to their thinning hair.

The user has been experiencing worsening hair loss despite using finasteride, minoxidil, and later switching to dutasteride. Despite normal bloodwork and consulting dermatologists, the hair loss continues without improvement.

Three months into using Minoxidil, finasteride, dermarolling, tretinoin, and saw palmetto shampoo, the user is seeing baby hairs on their hairline and is hopeful they will thicken. Another user reports that their own baby hairs have been getting thicker and longer over time.

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

Oral minoxidil can cause multiple facial hairs to grow from one follicle, known as Pili Multigemini, leading to ingrown hairs and zits. Users report increased facial and body hair growth, with some experiencing fewer issues after switching to dutasteride.

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

DutchFella1993 has been using a lotion with finasteride and minoxidil for hair regrowth with some success and is considering using ketoconazole shampoo daily to reduce scalp itchiness. There's concern about the harshness of daily shampooing and twice-daily lotion application, and one reply suggests that daily use of ketoconazole may damage hair and questions its effectiveness, while also noting that once-daily minoxidil application is sufficient.

Using a silicone shampoo brush with ketoconazole shampoo may increase hair shedding if used roughly. Hair that sheds during shampooing would have fallen out eventually.

Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.