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      community I can finally sleep at peace😔🙏

      in Satire  1674 upvotes 1 year ago
      The conversation humorously discusses various methods of applying minoxidil for hair loss, with some users suggesting oral minoxidil as a more convenient option despite potential side effects. The original poster jokes about using a red light helmet with mesotherapy needles for continuous minoxidil application.

      community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

      in Research/Science  13 upvotes 11 months ago
      BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

      community Best red light hair therapy device for someone already on min and fin? Looking to add LLLT to my stack.

      in Technology  12 upvotes 3 weeks ago
      The user is considering adding low-level laser therapy (LLLT) to their hair loss treatment routine, which already includes minoxidil, finasteride, and microneedling. They are debating between purchasing a cheaper LLLT device or investing in a more expensive, clinically-backed option, with concerns about the effectiveness and specifications of cheaper models.

      community Which dermaroller do y'all use?

      in Microneedling  26 upvotes 2 years ago
      The conversation is about recommendations for microneedling tools for hair loss, with users suggesting a dermastamp from Koi Beauty and the Derminator 2 with 12-needle cartridges.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 6 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 9 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Anyone using Finastopic (no pg Isdin)?

      in Product  2 upvotes 2 years ago
      The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Is injections with dermapen possible?

      in Microneedling  8 upvotes 1 year ago
      A user is considering using a dermapen with liquid solutions like minoxidil for hair loss as a cost-effective alternative to mesotherapy. They seek advice on the effectiveness and experience with such devices.

      community Combining Microneedling with LLLT

      in Research/Science  13 upvotes 1 year ago
      Combining microneedling with Low Level Laser Therapy (LLLT) for hair growth, with discussions on device legitimacy and effectiveness. Alternatives like PEMF and the use of oral and topical treatments such as dutasteride, minoxidil, and finasteride are also considered.

      community got my very first hair system :)

      in Hair Systems  378 upvotes 4 years ago
      User got a hair system after hair transplant and finasteride didn't meet their needs. Hair system cost $200, initial install $150, and user is satisfied with the results.

      community Did someone already tried scube3 ?

      in Technology  1 upvotes 2 years ago
      The conversation is about whether a doctor is needed for injections of a product called SCUBE3 for hair loss. No specific treatments were discussed.

      community Koreabeautics V2 Microneedling Scam in Reddit

      in Microneedling  38 upvotes 1 year ago
      A user warns against buying the Koreabeautics V2 microneedling pen, claiming it's marketed through fake success stories and is overpriced. Another user shares their experience, acknowledging the pen's quality but agreeing it's too expensive and reliant on frequent needle head replacements.

      community Anyone tried Thicair? thoughts?

      in Product 10 months ago
      Thicair is a product combining microneedling and subdural vitamins for hair loss, containing ingredients like Panax Ginseng Root Extract and Copper Tripeptide-1. Users are skeptical, with one calling it "quackery."

      community July 1st - Early H2 - Breezula

      in Treatment  1 upvotes 11 months ago
      Discussion on hair loss treatments, focusing on Breezula, with mentions of Minoxidil, finasteride, RU58841, Pyrilutamide, GT20029, and PP405. Breezula's effectiveness is uncertain, with some trials showing minimal regrowth.

      community HMI-115 when will it be available

      in Research/Science  15 upvotes 3 years ago
      The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

      community Do you recommend this derma stamp system

      in Treatment  128 upvotes 2 years ago
      The conversation is about the preference for using a derma stamp over a derma roller for hair loss treatment, with users discussing its efficiency, needle material, replacement frequency, and personal experiences. Specific treatments mentioned include microneedling with a derma stamp.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 8 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Solution vehicle used by compounding pharmacy

      in Research/Science  1 upvotes 2 years ago
      The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

      community Dermastamp only with carrier/essential oil blend

      in Microneedling  16 upvotes 3 years ago
      A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

      community Breezula is a good alternative

      in Research/Science  5 upvotes 1 month ago
      Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

      community My Hair System Journey, Part 4

       16 upvotes 7 years ago
      The user shares their experience with a hair system, noting no one noticed the change except their girlfriend. They discuss the learning curve, maintenance tips, and their satisfaction with the results, feeling more confident and optimistic.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 6 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community How long still for CB-03-01? (breezula)

      in Question  7 upvotes 6 years ago
      The conversation is about the release timeline for clinical trial results and the availability of Breezula, a hair loss treatment. The user is not comfortable buying it as a research drug from China.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  35 upvotes 3 years ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.