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      community Topical Pyrilutamide - Hormone Panel

      in Treatment  2 upvotes 2 years ago
      The user used 0.5 mL of 0.5 mg of Pyrilutamide for 60 days for hair loss, but didn't notice any hair growth. They shared their hormone panel results and are seeking advice on next steps.

      community Hydrocortisone helps with itch

       4 upvotes 8 years ago
      Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Oral minoxidil hypertension after stopping

      in General  48 upvotes 6 months ago
      The user switched from topical to oral minoxidil (5mg daily) a year ago, saw no improvement, and experienced chest pain and trouble sleeping after stopping. They are considering whether to resume and taper the dosage due to stress and anxiety.

      community Spironolactone, what do you think?

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

      community switching to Kirkland Min from Online Pharmacy min?

      in Minoxidil  2 upvotes 2 years ago
      The user is considering switching from an expensive topical hair loss treatment containing 8% Minoxidil, 0.3% Finasteride, Retinoic Acid, and Hydrocortisone to a cheaper Kirkland brand Minoxidil. They are concerned about the effectiveness of the lower concentration and the absence of additional ingredients.

      community Finasteride influence on other hormones

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

      community Using ketoconazole shampoo daily?

      in Ketoconazole  24 upvotes 4 months ago
      Using ketoconazole shampoo daily can dry out hair, and most users recommend using it 1-2 times a week with conditioner. Some users combine it with minoxidil and finasteride for better hair growth results.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

      in Research/Science  5 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

      community Balding, stressed and depressed

      in Chat  63 upvotes 3 years ago
      A 22 year old man who is experiencing hair loss, thinning and dry scalp, has tried treatments such as finasteride and minoxidil, and other users sharing their experiences with similar issues.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Success: My Doc prescribed me 0.1% Alfatradiol

      in Treatment  13 upvotes 1 year ago
      A user shared their success in getting a prescription for 0.1% Alfatradiol, a topical treatment for hair loss similar to finasteride but with fewer side effects. They found a pharmacy to compound it and will update on the results.

      community Accelerated Hair Loss from Creatine

      in Finasteride/Dutasteride  133 upvotes 7 months ago
      Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.

      community Optimal dose for topical Melatonin

      in Treatment  5 upvotes 2 years ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

      community is my multi vitamin a high dose ?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      User experienced hair loss after weight loss and started using finasteride 1mg and a multivitamin called HAIRGRO. They noticed increased oily skin and sebum production and are unsure if they should continue the multivitamin.

      community Topical Vitamin C trials for hair loss?

      in Treatment  6 upvotes 5 months ago
      Topical high-dose vitamin C is discussed as a potential treatment for hair loss due to its ability to inhibit DHT and reduce histamine. Some users express skepticism about its effectiveness compared to treatments like finasteride.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community 1 year of min+fin+ketoconazole

      in Progress Pictures  1058 upvotes 2 years ago
      The user has been using minoxidil daily, finasteride three times a week, and ketoconazole 1-3 times a week for a year to treat hair loss, resulting in noticeable hair regrowth at the hairline and temples, with minor side effects like itching and dandruff. They started with minoxidil a month before the other treatments and experienced an initial shedding phase for about six weeks.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 9 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community How’s RCH-01 doing?

      in Treatment  6 upvotes 6 years ago
      RCH-01's progress is uncertain, and there's skepticism about its effectiveness. Users are losing hope in this treatment.

      community My Bloodwork — After 4 Months On Finasteride.

      in Finasteride/Dutasteride  7 upvotes 4 months ago
      The user is on Finasteride for hair loss, taking 0.5mg daily, and plans to reduce the dose to 0.25mg while making lifestyle changes to lower prolactin, SHGB, and cortisol. They will retest in 90 days to assess progress and are open to advice.

      community Is Ketoconazole a big factor in preventing hairloss?

      in Ketoconazole  41 upvotes 1 year ago
      Ketoconazole shampoo may help with scalp health and inflammation but is not a substitute for DHT blockers like finasteride. It is generally considered a minor addition to hair loss treatment, with varying opinions on its effectiveness.