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Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

The user shared progress pictures showing hair regrowth over 55 days. They used 1mg finasteride, a 1mm dermaroller once per month, and 5% minoxidil twice daily.

A 38-year-old man from Poland, balding for 15 years, shared his hair regrowth progress after 4 months of using finasteride (fin), minoxidil (min), micro-needling, and infrared light treatments. He recently switched from finasteride to dutasteride.

The user experienced initial improvement in hair loss with oral finasteride and minoxidil but later faced increased shedding and thinning. They switched to dutasteride, hoping for better results, while continuing topical minoxidil.

The user shared their 6-month progress using finasteride and minoxidil for hair loss, noting improvements and reduced shedding. They decreased their minoxidil dosage from 10% to 5% and no longer need biotin, with no side effects from finasteride.

A 26-year-old male with grade 3 hair loss is using 2.5 mg oral minoxidil, 1 mg finasteride, 5% minoxidil, ketoconazole shampoo, and kLM d3. He plans to post progress pictures every 6 weeks and is seeking suggestions.

A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.

The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

A 20-year-old shared progress pictures after 4 months on finasteride and 5% topical minoxidil, showing significant hair regrowth. Users discussed their experiences with similar treatments, side effects, and application routines.

A user shared their positive experience with MoriTint, a Korean scalp micro pigmentation technique that enhances the appearance of hair density without being permanent. They now offer this service in Los Angeles and emphasize its benefits for those with thinning hair, while clarifying it is not suitable for those with significant hair loss or baldness.

A 31-year-old Indian man shared his 6-month hair loss progress using oral finasteride and topical minoxidil, showing noticeable improvement. Replies were positive, noting thicker hair and a better hairline.

The user is experiencing excessive hair thinning and is unsure of the cause. They are seeking opinions on treatments like Minoxidil, finasteride, and RU58841.

A 35-year-old male experiences rapid hair loss on his head and body despite normal test results for testosterone, thyroid, and vitamins. He previously used topical minoxidil and retinol, and doctors have been consulted without finding a clear cause.

The user shared a 3-month update on their hair loss treatment using finasteride, minoxidil, microneedling, and ketoconazole shampoo, later switching to dutasteride. They plan to evaluate progress after a year and consider a hair transplant.

The user shared progress pictures showing significant hair regrowth using Minoxidil and a dermapen, expressing concerns about potential side effects of finasteride due to low testosterone levels. Another user reported increased testosterone and no side effects from finasteride, with improved libido.

User shared progress pictures after 2 months of using 1mg finasteride for hair loss. They are seeking feedback on any improvement.

CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

A person shared their hair transplant experience, mentioning complications like excessive bleeding and density anxiety, and is using finasteride and minoxidil chewables. They traveled to Turkey for the procedure, paid around $3800, and are considering Mexico for future treatments; nicotine use is a concern for their recovery.

Chris's hair transplant looks better, but the hairline is criticized for being too straight and unnatural. Some recommend using finasteride and minoxidil for maintenance.

A user shared a 3-month progress picture showing hair regrowth using 5% Minoxidil and microneedling, but not taking Finasteride. Some users are surprised by the quick results, and there's a discussion about the effectiveness of frequent deep microneedling.

Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.

Trying out a new exosome treatment for male pattern baldness, in addition to increasing vitamin intake and using existing treatments such as Nizoral and scalp drops. The user has no expectations that the new treatment will work but is giving it a try anyway.

The user shared a 9+ month hair loss treatment progress with 1mg finasteride in the morning, 2.5mg oral minoxidil at night, and vitamin A spray at night, noting the importance of seeing a dermatologist early as their cousin started treatment too late for it to be effective.

A 57-year-old user shared their one-year hair loss treatment progress using Minoxidil, Finasteride, Dutasteride, RU58841, KX-826, Keto shampoo, vitamins, and an iRestore helmet. They are considering simplifying their regimen to prescribed medications and feel uncertain about continuing despite seeing some progress.

User shared 6-month hair loss treatment update with Dut 3x/week, oral min, and dut+prp mesotherapy. Experienced positive results, no side effects, and recommends the regimen.

A user shared their first progress picture after 60 days on finasteride for hair loss, having previously used minoxidil and other treatments. They thanked the community for discussions that encouraged them to try finasteride.

PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

A user reported significant hair regrowth after 4 months using finasteride and minoxidil, with no major side effects. They are considering oral minoxidil and use microneedling and ketoconazole shampoo.

The user shared progress pictures showing hair regrowth after increasing the dose of topical Minoxidil and adding Finasteride. Replies indicate positive feedback and encouragement, noting visible improvement in the hairline.

Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.