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      community Can topicals cause a never ending shed?

      in Treatment  2 upvotes 2 years ago
      The user reintroduced RU58841 and noticed increased shedding and visible thinning. They have also been using dutasteride and oral minoxidil for 2 years.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 6 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  236 upvotes 7 months ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community Diffuse thinning is so brutal.

      in Styling  73 upvotes 3 years ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community 7.5 Months on Min + Fin — Progress Pics + Questions (Crown, Temples, Folliculitis)

      in Is this regrowth?  76 upvotes 3 months ago
      The user has been using minoxidil and finasteride for 7.5 months to address hair thinning, particularly at the crown and temples, and is considering additional treatments like tretinoin and dermastamping despite having chronic scalp folliculitis. They are experiencing progress but are concerned about side effects and the effectiveness of treatments on temple regrowth.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.
      Receding hairline / temples - asking for advice

      community Receding hairline / temples - asking for advice

      in General  114 upvotes 6 months ago
      The user is experiencing hair loss and has been using RU58841 but is considering pyrilutamide and minoxidil, avoiding finasteride due to side effects. Another user suggests finasteride or dutasteride as essential, possibly in topical form, while dismissing saw palmetto as ineffective.

      community 17M biotin and minoxidil hair regrowth progress

      in Progress Pictures  83 upvotes 2 years ago
      A user's hair regrowth journey using biotin and minoxidil after initial treatments with Nizoral shampoo and Ketoconazole serum didn't work. The comments suggest the hair loss might not be male pattern baldness (MPB), but possibly Alopecia Areata, an autoimmune disorder, and recommend getting a second opinion and considering other treatments like corticosteroids.
      1.5 years topical min and fin where do I go from here

      community 1.5 years topical min and fin where do I go from here

      in General  69 upvotes 1 year ago
      The user has been using topical minoxidil and finasteride for 1.5 years, which has thickened existing hair but left some areas thin. They suspect the treatment may be causing dandruff or seborrheic dermatitis and are seeking advice.

      community Getting PP405. Now…. or as soon as possible

      in Research/Science  145 upvotes 11 months ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community Progress pictures over 7 months

      in Progress Pictures  51 upvotes 1 year ago
      The user reported modest hair improvement using 1 mg finasteride daily, topical minoxidil twice daily, and weekly microneedling over seven months. Other users discussed their own experiences and encouraged patience, with some suggesting additional treatments like dutasteride and dermarolling.

      community Help! Minoxidil or Duta to avoid Shed of long hair.

      in Female  8 upvotes 1 year ago
      The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

      community Before and after adding pyrilutamide and alfatrodial

      in Progress Pictures  69 upvotes 1 month ago
      A user shared their experience with hair loss treatments, using minoxidil, pyrilutamide, alfatrodial, and nizoral to improve hair density and thickness. They reported positive results without side effects and emphasized the importance of consistency with topical treatments.

      community 18M progression pt.3 (6 months)

      in Progress Pictures  744 upvotes 3 years ago
      User started balding at 16 and began treatment at 18, using RU58841, minoxidil, derma rolling, and peptides. After 6 months, they experienced significant hair regrowth and are happy with the results.

      community 10 months on Topical Fin/Min Progress

      in Progress Pictures  11 upvotes 2 years ago
      The user tried non-finasteride treatments for a year with little success, but has seen some improvement in hair thinning after 10 months using topical finasteride/minoxidil. They also use microneedling, Nizoral, rosemary/castor oil treatments, and maintain a nutrient-rich diet.

      community Progress with low-dose topicals

      in Research/Science  4 upvotes 1 month ago
      The conversation discusses using low-dose topical finasteride, specifically 0.005% and 0.01%, for hair regrowth, with some users considering increasing the concentration for better results. Users share experiences with different dosages and combinations, including minoxidil, and discuss the effectiveness and availability of these treatments.

      community Does this look like regrowth??

      in Satire  274 upvotes 7 months ago
      Hair regrowth using oral minoxidil, finasteride, and microneedling. User reports progress with no side effects and improved hair density.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.