HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
The user is experiencing hair loss despite using dutasteride, minoxidil, and ketoconazole shampoo, and is concerned about continued shedding. Suggestions include checking for nutrient deficiencies, consulting a dermatologist, and considering other potential causes like seborrheic dermatitis or telogen effluvium.
A user shared their 4-month progress using a topical solution with 5% minoxidil and 0.1% finasteride, applied twice daily. They reported good results despite occasional missed applications.
The conversation discusses hair loss treatments, specifically the use of 5% topical minoxidil, with considerations for adding finasteride or dutasteride. Concerns about side effects, such as unwanted body hair growth from oral minoxidil, are also mentioned.
The user shared progress after 3.5 months using topical finasteride (0.2%) and minoxidil (5%), noting thicker hair despite a receding hairline. They plan to consider a hair transplant in the future and found applying treatments easier on a shaved head.
The user has been using oral finasteride and topical minoxidil for 4 months and is questioning if there's regrowth. Responses suggest that diffuse thinning takes longer to show results, but there is some progress noted.
Clascoterone 5% shows potential for hair thickening and darkening, especially when combined with treatments like finasteride. It may be a good alternative for those who experience side effects from other treatments.
A user shared their 3-month progress using RU58841, 10% minoxidil, and microneedling every two weeks for hair loss. They found the new minoxidil sprayer effective for applying the treatment across the scalp.
The user has been using 0.25% topical finasteride and 5% minoxidil for 1.5 years with significant hair improvement and plans to start microneedling and possibly switch to oral finasteride for better long-term results. They are happy with the progress but seek more hair density and have not experienced any side effects.
A 43-year-old male with advanced hair loss is experimenting with alternative treatments, including red light therapy, microneedling, scalp massages, an oil mix, and ketoconazole shampoo, after previously experiencing side effects from finasteride and minoxidil. He noticed some minor changes with red light therapy but remains skeptical about significant improvement.
A user's 18-month hairline progress using minoxidil, finasteride, Nizoral, microneedling, and scalp massage. They share their routine and discuss treatment effectiveness and photo order confusion.
Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.
User shared 3-week progress using Pyrilutamide once a day for hair loss. Another user shared their 3-month progress with 0.25% concentration Pyrilutamide, experiencing rollback of 4 years in 3 months.
Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.
An 18-year-old experiencing mild hair thinning is prescribed ketoconazole shampoo, clobetasol, and a solution with minoxidil, finasteride, and tretinoin. They are hesitant to start finasteride due to concerns about systemic absorption and its impact on facial hair development.
A person using Minoxidil, Finasteride, Microneedling, and recently added Tretinoin is experiencing heavy shedding and thinning hair. They suspect Tretinoin has made them respond to Minoxidil and are seeking others with similar experiences.
The conversation is about how to effectively apply 1mL of a topical hair loss treatment, Pyrilutamide, to cover the entire scalp. One user suggests making a 2.5 mg/mL solution and using 2mL for better coverage.
User phoenixblue asked about hair fiber products like Toppik and if they cause hair loss by clogging pores. Replies suggested that Toppik is safe, but effectiveness varies; some users experienced no hair loss, while others had issues with color or sweating.
A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.
The conversation discusses difficulty in distinguishing between new hair growth and thinning hair at the temples after using microneedling and a rosemary peppermint topical for four weeks. The advice given is to wait a few months to see if the hairs grow out to determine their nature.
The user has experienced limited hair regrowth using 1mg oral finasteride, topical minoxidil foam, and occasional dermarolling since August 2023. They are considering switching to dutasteride, adding oral minoxidil 2.5 mg, and RU58841 to improve results.
The user experienced hair improvement using minoxidil, microneedling, and finasteride, with noticeable progress at the temples. They attribute most gains to minoxidil and plan to continue treatments, noting no significant side effects except increased libido.
The user shared progress pictures showing significant hair regrowth using Minoxidil and a dermapen, expressing concerns about potential side effects of finasteride due to low testosterone levels. Another user reported increased testosterone and no side effects from finasteride, with improved libido.
The user shared progress pictures after using topical finasteride, minoxidil, and tretinoin for about 9 months, along with weekly microneedling, cold showers, and a diet free of processed foods. They reported no side effects.
A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.
User shared progress pictures after 5 months using 5 mg oral minoxidil, a topical formula with 8% minoxidil, 0.1% finasteride, and 0.01% tretinoin, and a 1.5 mm Dermapen every other week. The conversation discusses the effectiveness of this regimen for hair loss.
Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.
Hair loss progress discussed with 4.5 months on topical fin (0.025% liposomal). User uses rosemary oil for scalp health, and others think there might be some thickening or maintenance.