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      community Low Estradiol while on 1mg Fin, what should I do?

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.

      community Thoughts on Latanoprost For Miniturization?

      in Treatment  3 upvotes 3 years ago
      User discusses Latanoprost as potential hair loss treatment and considers combining it with oral minoxidil for better results. Seeking opinions on effectiveness and expense.

      community Stumbled on some research

      in Research/Science  6 upvotes 5 years ago
      Elevated PGD2 levels in bald scalp tissue may contribute to hair loss, and treatments like castor oil, finasteride, and minoxidil are discussed as potential solutions. Some users explore alternatives like oral castor oil and cetirizine for those who cannot use finasteride.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 10 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 2 years ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Starting Pyrilutimide 5% Update

      in Treatment  1 upvotes 2 years ago
      The user started using Pyrilutamide 5% for hair loss and has not experienced side effects after two days. They previously had side effects from Fluridil and topical Minoxidil 5%, and their hair continued thinning with topical Spironolactone.

      community Why is there so much negativity around pyrilutamide?

      in Research/Science  19 upvotes 11 months ago
      Pyrilutamide is discussed as an effective hair loss treatment by some users, despite skepticism due to limited data and underwhelming trial results. Users compare it to finasteride, minoxidil, and RU58841, with some expressing interest in its potential as an adjunct treatment.

      community Serenoa repens (Saw palmetto)

      in Chat  1 upvotes 1 month ago
      Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

      community 10 months treating MPB - I am happy with these results

      in Progress Pictures  8 upvotes 8 months ago
      A 26-year-old man shared his positive results after 10 months of treating male pattern baldness using a regimen that includes Estradiol Enanthate, DHPA, Bicalutamide, Dutasteride, oral and topical Minoxidil, and a dermaroller. He experienced mild gynecomastia and reduced body hair as side effects but was satisfied with the outcome.

      community Optimal dose for topical Melatonin

      in Treatment  4 upvotes 2 years ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

      community PP405 mechanism question - looking for discussion

      in Treatment  7 upvotes 2 weeks ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community My experience with Pyrilutamide

      in Update  3 upvotes 2 years ago
      The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 3 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community New article on PP405..........

      in Research/Science  109 upvotes 11 months ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Finasteride and hormonal tests

      in Finasteride/Dutasteride 3 months ago
      A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

      community pictures before I started pyrilutamide (repost)

      in Progress Pictures  124 upvotes 3 years ago
      Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

      community Does Pyrilutamide lowers sebum production?

      in Treatment  2 upvotes 4 months ago
      Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.