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      community Nest topical compound stack to fight hair loss

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 11 months ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community How can my DHT be so low without Finasteride on cycle?

      in Finasteride/Dutasteride 4 weeks ago
      A user is curious why their DHT levels are not higher despite using 400mg of testosterone without finasteride, and wonders if zinc or GHK-Cu injections could be influencing this. Another user suggests that more testosterone typically leads to more DHT, but the user might be fortunate not to exceed normal DHT levels.

      community Update: Chest discomfort from RU58841

      in Update  35 upvotes 2 years ago
      A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Effect of melatonin on aromatase expression

      in Update  5 upvotes 4 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

      community 14 Months Dut/Minox/Microneedling + 13 Months HRT

      in Transgender  36 upvotes 2 months ago
      The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.

      community Is there any new drug that looks promising ?

      in Research/Science  26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

      in Research/Science  3 upvotes 2 years ago
      The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

      community Ferritin, iron and testosterone

      in Chat  4 upvotes 2 months ago
      Dutasteride may affect testosterone levels, leading to high ferritin and iron levels, which can cause hair loss. High ferritin might be linked to past heavy drinking or hemochromatosis.

      community The real stack, the only things you really need.

      in Treatment  1 upvotes 1 year ago
      The conversation discusses a hair loss prevention regimen using a custom topical treatment with Dutasteride, Minoxidil, Latanoprost, Cetirizine, Tretinoin, Vitamin D3, and caffeine, along with supplements like iron, selenium, vitamin D, and vitamin B. The user advises against expensive treatments like LLLT caps and unnecessary natural supplements.

      community Rate my hair loss stack as of 3/18

      in Treatment  1 upvotes 3 months ago
      The conversation is about a hair loss treatment regimen including finasteride, oral minoxidil, Stemoxydine, a multi-peptide serum, and ketoconazole. A suggestion was made to add dermastamping and tretinoin.

      community Got the bloodwork results and it’s interesting

      in Treatment  15 upvotes 2 months ago
      The user has high DHT levels despite using dutasteride, which may not be effective due to potential damage or spoilage. They are considering a hair transplant if DHT levels don't decrease after two years.

      community Any good experiences with Alfatradiol ?

      in Treatment  4 upvotes 6 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Dont know what the hell is going on.

      in Chat  6 upvotes 1 year ago
      The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

      community Bicalutamide and muscles growth

      in Female  8 upvotes 1 year ago
      A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

      community Is this regrowth? My doctor took these photos and said I looked better.

      in Satire  142 upvotes 1 year ago
      The conversation humorously discusses an extensive and exaggerated hair loss treatment regimen, including finasteride, dutasteride, minoxidil, pyrilutamide, RU58841, and various other therapies. Despite the numerous treatments, the effectiveness is questioned, and the user humorously considers adding more minoxidil.

      community Injecting estrogen for hairline regrow

      in Chat  267 upvotes 1 year ago
      A user plans to undergo a temporary MtF transformation to regrow hair, using estrogen, RU58841, and Dutasteride, then revert with testosterone. Many users criticize the plan, suggesting alternatives like hair transplants, and emphasize that estrogen is not a reliable solution for hair regrowth.

      community How. can I counteract the rapid hair loss caused by steroids?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The conversation is about a person experiencing hair loss from steroid use, considering treatments like RU58841, dutasteride, and Nizoral, while avoiding finasteride and Minoxidil due to concerns about hormones and hypertension. The consensus suggests using dutasteride or finasteride, as Nizoral alone is not effective.