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      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 10 months ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community Dermarolling is a bit sad innit?

      in Microneedling  232 upvotes 4 years ago
      Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

      community Sweet Lord my DHT itch is finally gone

      in Chat  49 upvotes 2 years ago
      Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 1 year ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community What is going on with my scalp?

      in Female  25 upvotes 2 years ago
      A user named Mmherak is experiencing hair loss, with low B12 and iron deficiency, and has been recommended minoxidil and spironolactone by dermatologists. Other users suggest seborrheic dermatitis or dandruff, recommending treatments like Nizoral shampoo, ketoconazole, and Selsun Blue.

      community just saw my hair under harsh sunlight and devastated..

      in Chat  121 upvotes 1 year ago
      The conversation discusses hair loss struggles and treatments, including oral minoxidil, oral finasteride, and RU58841. Users share experiences and advice, suggesting options like topical minoxidil, microneedling, hair transplants, and scalp micropigmentation.

      community Why is no one talking about alfatradiol?

      in Treatment  24 upvotes 1 year ago
      Alfatradiol is discussed as a hair loss treatment with minimal side effects, but its effectiveness is debated, and it's not widely known or available outside Germany. Some users report side effects like gyno and ball ache, while others find it effective in stopping shedding and itching.

      community Don’t know what is happening to me

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user experienced significant hair improvement with minoxidil and finasteride but later faced shedding and diffused thinning after developing seborrheic dermatitis. They are seeking advice after trying treatments like ketoconazole, coal tar shampoos, fluconazole, and hydrocortisone cream.

      community Vitamin Deficiency: “Severely” Low on Vitamin D

      in Update  15 upvotes 2 years ago
      A user experiencing significant hair loss found they had a severe vitamin D deficiency and was prescribed 50,000IU vitamin D pills, likely to be taken weekly. They are questioning if the deficiency could be the cause of their hair loss and if correcting it could stop the shedding and improve hair recovery.

      community M20 Vitamin D Deficiency and Hair Thinning

      in General  75 upvotes 11 months ago
      A 20-year-old is experiencing hair thinning due to vitamin D deficiency and has completed a vitamin D prescription without seeing improvement. Suggestions include waiting a few months for potential regrowth or considering treatments like minoxidil or finasteride for androgenetic alopecia.

      community Redness and flaking from topical minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Topical minoxidil with tretinoin is causing redness, stinging, and flaking on the scalp. Reducing application frequency and using anti-dandruff shampoo may help alleviate symptoms over time.

      community Got into argument with my dermatologist, AITA?

      in General  198 upvotes 4 months ago
      A 20-year-old male is frustrated with his dermatologist for refusing to prescribe DHT blockers like finasteride or dutasteride, instead pushing for a hair transplant despite ongoing hair thinning. The user feels dismissed and unreasonably treated, and is advised by another user to find a better dermatologist and consider finasteride or dutasteride for effective treatment.

      community Am I crazy or is this recovery?

      in Is this regrowth?  134 upvotes 1 year ago
      The user is experiencing sudden hair loss and is considering micro-needling, low-level light therapy, iron supplements, folihair, and Omega 3. They are hesitant to start finasteride, suspecting the hair loss might be due to telogen effluvium from a past COVID-19 infection.

      community Can't help but feel somethings wrong (MtF 18)

      in Transgender  4 upvotes 1 day ago
      The user is experiencing hair loss and is using treatments like finasteride, minoxidil, and hormone replacement therapy (estradiol enanthate injections) to address it. They are advised to be patient with the treatments and consider using a dermapen for microneedling.

      community Request for advice, feedback...

      in Chat  2 upvotes 10 months ago
      The conversation discusses hair loss treatments for a woman experiencing androgenetic alopecia and seborrheic dermatitis, with suggestions including low-dose oral minoxidil, dutasteride, and hormone replacement therapy. The user is seeking advice due to intolerance to spironolactone and topical minoxidil, and concerns about low testosterone and DHT levels.