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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Huge holes on donor area of scalp is this even normal?

      in Transplants  106 upvotes 2 years ago
      The conversation is about a person experiencing significant hair loss in the donor area after a hair transplant, with others suggesting it might be shock loss. The person is taking oral minoxidil and dutasteride to help with the issue.

      community Coffee and androgenetic alopecia

      in Research/Science  12 upvotes 2 years ago
      The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.

      community Intense hairfall, please help

       2 upvotes 11 years ago
      A 22-year-old experiencing intense hair loss across the scalp seeks advice, considering factors like nutrition and genetics. Suggestions include checking vitamin, mineral, and thyroid levels.
      What should i do? ideas? stressed-ish

      community What should i do? ideas? stressed-ish

      in General  106 upvotes 11 months ago
      A 44-year-old is experiencing rapid hair thinning after weight loss, despite using finasteride for two years. They have added minoxidil, vitamins, ketoconazole shampoo, derma stamping, and are considering PRP treatment while slowly introducing dutasteride.
      Struggling with Chronic Hair Loss Despite Treatments at 20

      community Struggling with Chronic Hair Loss Despite Treatments at 20

      in Basic Questions  180 upvotes 1 week ago
      A 20-year-old male has been experiencing hair loss since age 16 and has tried various treatments including topical minoxidil, topical and oral finasteride, and oral dutasteride with minoxidil, but has not seen significant improvement. He is currently using 1.5mg dutasteride and 5mg oral minoxidil daily, along with derma penning, and is seeking advice on regrowing hair to avoid using hair fibers.

      community We need to talk about DHT itch

      in Treatment 3 years ago
      DHT Itch and its link to balding, with various treatments such as finasteride being discussed. Members shared their experiences of scalp itch before and after taking 5AR inhibitors, and potential underlying causes such as seborrheic dermatitis were discussed.

      community Just passed by a homeless guy!

      in Chat  190 upvotes 1 year ago
      Hair loss treatments include finasteride, minoxidil, alfatradiol, vitamins, red light therapy, ketoconazole shampoo, meditation, green tea, leg workouts, and silk pillows. Genetics is emphasized as the primary factor in hair health, with some humor about unconventional methods like drug use affecting hair loss.

      community Hairline hairs wont grow past a certain length :(

      in Minoxidil  1 upvotes 11 months ago
      A user shared their experience with hair loss treatments, including topical minoxidil, finasteride, RU58841, and microneedling, noting significant hair regrowth except at the hairline. They plan to start oral minoxidil and switch to a combination treatment, while another user mentioned that some miniaturized hairs may not fully recover.

      community Shampoo without salicylic acid

      in Product  2 upvotes 9 months ago
      A user is seeking a hair-loss shampoo without salicylic acid due to an allergy. Recommendations include using Finasteride, Minoxidil, and Nizoral Anti-Dandruff Shampoo (ketoconazole), while avoiding Nizoral Scalp Psoriasis Shampoo & Conditioner.

      community Topical Prednisolone as hair loss treatment?

      in Treatment  1 upvotes 4 years ago
      A user is concerned about using Alpicort, which contains Prednisolone and Salicylic Acid, for male pattern baldness. They are unsure if it will help or worsen their condition and are seeking advice.

      community For those on TRT and suffer from a more aggressive type of (AGA) hairloss, what are your hair safe protocols?

      in Chat  6 upvotes 3 years ago
      People on testosterone replacement therapy (TRT) with aggressive androgenetic alopecia (AGA) discuss using Dutasteride or Finasteride, sometimes combined with topical treatments like RU58841 or CB-03-01 (Breezula), to prevent hair loss. Concerns about side effects and costs of certain treatments are mentioned, with one individual sharing their experience of slowed hair loss using Finasteride alone.

      community Concern about my hair loss escalation

      in Transgender 1 year ago
      The user is experiencing significant hair loss and has tried treatments like PRP therapy, topical and oral Minoxidil, Finasteride, and dietary changes, with limited success. They are concerned about losing more hair before a scheduled hair transplant and are advised to postpone the transplant to allow medications more time to work.

      community Dude single handedly beat baldness

      in Is this regrowth?  36 upvotes 3 weeks ago
      A user claims to have reversed baldness, possibly due to telogen effluvium recovery after weight loss. Others discuss the potential success of using GHK-Cu for hair regrowth.

      community Desperate for help - Dread shed since 5 months!

      in Minoxidil  1 upvotes 1 year ago
      The user is experiencing severe hair loss after starting Minoxidil 5% and is seeking advice, as their hair loss worsened following a second COVID infection. Despite normal hormone and vitamin levels, the user is considering additional treatments like Ketoconazole shampoo, massages, and low-level laser therapy.

      community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

      in Progress Pictures  15 upvotes 1 month ago
      The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

      community Does anyone think their hair loss is thyroid related?

      in Chat  11 upvotes 1 year ago
      Hair loss may be linked to thyroid issues, with some individuals noticing changes in hair texture when taking substances affecting the thyroid. Treatments mentioned include a topical mix of finasteride, minoxidil, and tretinoin, along with microneedling.

      community Scalp, eyebrow, eyelash and pubic hair loss.

       7 upvotes 8 years ago
      The user experienced significant hair loss on the scalp, eyebrows, eyelashes, and pubic area, along with itchy, flaky skin and red patches. They have a history of eczema and dermatitis and suspect that stopping shampoo use and taking Ritalin may have contributed to the issue.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 2 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community Still loosing hair on 1mg FIN ( 11 months) and 0.5mg DUT every alternate days (30days)

      in Update  3 upvotes 2 months ago
      The user is experiencing continued hair loss despite using finasteride, dutasteride, and minoxidil, and is advised to improve diet, check for deficiencies, and consider other treatments like microneedling. Suggestions include sticking with the current regimen, considering a hair transplant, or accepting hair loss and shaving.

      community Brutal Hair loss At 19: Help+Treatment Questions

      in Chat  6 upvotes 4 years ago
      A 19-year-old experiencing hair loss since 17 uses finasteride, minoxidil, dermaroller, ketoconazole shampoo, and oral castor oil, but sees little improvement. They seek advice on adding an anti-androgen, considering alfatradiol.
      Someone please save me (19M)

      community Someone please save me (19M)

      in General  91 upvotes 11 months ago
      A 19-year-old is experiencing hair loss and shedding despite using Dutasteride and topical Minoxidil for six months. They are concerned about potential infections like folliculitis and are considering stopping the treatments due to stress and hair loss from various areas, including eyebrows and eyelids.

      community dutasteride 9 months, nonstop hair loss

      in Finasteride/Dutasteride  31 upvotes 3 years ago
      Experiencing continual nonstop hair loss despite using dutasteride for 9 months, and the possible causes behind it being discussed such as nutritional deficiencies, elevated cortisol, vitamin D deficiency or other problems. Other solutions such as minoxidil and finasteride have been suggested.