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      community RU58841, 8% HPLC-MS done by jano, they legit

      in Research/Science  7 upvotes 4 years ago
      The conversation is about testing the effectiveness of RU58841 for hair loss, with the user planning to increase their dose to 30 mg per day along with 20 mg of Minoxidil. The test results showed approximately 70 mg/ml, which the user considers a good result.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Procyanidin B2 Supplement

      in Research/Science  13 upvotes 5 years ago
      User seeks Procyanidin B2 supplement source and asks for dosage comparison. Another user requests study details and apple type importance.

      community 0-4 months 5mg min, 1.1mg fin, 1mg biotin

      in Progress Pictures  6 upvotes 7 months ago
      The user has been using 5mg Minoxidil, 1.1mg Finasteride, and 1mg Biotin for four months to address hair loss. They haven't noticed significant improvement yet but are documenting progress with monthly pictures.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  362 upvotes 2 years ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community Topical fin/minox + nizo shampoo and microneedling

      in Treatment  1 upvotes 2 months ago
      The user is using topical finasteride, minoxidil, nizoral shampoo, and microneedling for hair regrowth but hasn't seen results after 2-3 weeks. They added tretinoin to their routine and are advised to wait a few months for potential changes.

      community Is there any new drug that looks promising ?

      in Research/Science  26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Anyone tried CB-03-01?does it work ?

      in Research/Science  2 upvotes 10 months ago
      CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

      community Success: My Doc prescribed me 0.1% Alfatradiol

      in Treatment  13 upvotes 1 year ago
      A user shared their success in getting a prescription for 0.1% Alfatradiol, a topical treatment for hair loss similar to finasteride but with fewer side effects. They found a pharmacy to compound it and will update on the results.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 4 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community 1yr on fin and min. I guess im not bald anymore.

      in Update  203 upvotes 3 months ago
      A user shared their successful hair regrowth experience using 1.25mg finasteride daily, alternating oral and topical minoxidil, and weekly dermarolling. They reported significant improvement in their hairline and crown coverage over a year, with minimal side effects.

      community 5 months on Fin 1.25mg + Min 5% + Nizoral 2 x week

      in Progress Pictures  80 upvotes 2 years ago
      The conversation is about a user's successful hair regrowth after 5 months of using 1.25mg Finasteride, 5% Minoxidil, and Nizoral twice a week. The user, aged 28, experienced shedding in the first 6 weeks but has seen significant improvement since.
      Help me interpret my bloods

      community Help me interpret my bloods

      in General  65 upvotes 1 year ago
      The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

      community 2 year anniversary of Fin only - M48

      in Is this regrowth?  212 upvotes 1 year ago
      A 48-year-old man has been using finasteride at 1mg three times a week for two years, seeing some hair regrowth but noting lighting affects appearance. He is considering adding minoxidil but is concerned about shedding.

      community 6 month update of 1 mg fin only

      in Progress Pictures  30 upvotes 2 years ago
      A user shared a 6-month hair loss progress update using 1 mg finasteride, plans to start minoxidil and RU58841 due to severe shedding, and seeks advice. Others suggest maintaining treatment, switching to different medications, and considering more aggressive treatments due to strong genetic predisposition to baldness.

      community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

      in Research/Science  4 upvotes 2 years ago
      The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

      community RU58841 - Has anyone tried it before?

      in Research/Science  8 upvotes 1 month ago
      RU58841 is discussed as an effective hair loss treatment, with some users experiencing regrowth and reduced shedding, but concerns about safety and sourcing are raised. Users advise against purchasing from Amazon, recommending reputable sources and cautioning about potential side effects like cardiovascular issues.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 6 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 8 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Doctors won't let me try bicalutamide or fin

      in Female  6 upvotes 5 years ago
      Hair loss treatments discussed include 200mg Spiro, bicalutamide, and finasteride. Endocrinologist advises against bicalutamide and finasteride due to potency and risks.

      community 1 Year on Fin, 2 months on Min

      in Progress Pictures  33 upvotes 2 years ago
      The user has been using 1mg finasteride daily, 0.05% tretinoin, and 5% topical minoxidil for hair loss. They've seen hairline recession with minoxidil but also new baby hairs, indicating a positive response.