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      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community 8 months of 1mg fin EOD and 1ml of topical min ED

      in Progress Pictures  185 upvotes 1 year ago
      The user experienced significant hair regrowth using 1mg finasteride every other day and 1ml topical minoxidil daily, with initial shedding but improvement by three months. Microneedling was also used, with adjustments to frequency and needle length for better results.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  31 upvotes 6 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community TH07 by Triple Hair entering phase III trial

      in Research/Science 2 months ago
      A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

      community Pyrilutamide - Worth it if can’t use Fin?

      in Research/Science  4 upvotes 1 year ago
      Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

      community Microneedling makes a difference. Non responders, please read

      in Microneedling  66 upvotes 2 years ago
      A 48-year-old who had been thinning since 25 and reached NW4-5 baldness saw no improvement with 1mg/day finasteride and 5% minoxidil twice a day after 8 months. After copying another person's routine, they now use 0.5mg finasteride, ketoconazole shampoo weekly, daily microneedling with 0.5mm and 1mm once a week, and apply minoxidil twice daily, resulting in baby hairs on their bald spot and temples after three months.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 3 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  4 upvotes 1 year ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community 77 days fin + min + microneedling - hyper responder?

      in Progress Pictures  16 upvotes 10 months ago
      A user shared impressive hair growth results after 77 days using oral finasteride, topical minoxidil, and weekly microneedling. They reported thicker, darker hair and minimal shedding, with treatment costs around 30 euros per month.

      community Microneedling included as part of Big 4?

      in Question  7 upvotes 8 years ago
      Microneedling is considered an important addition to hair loss treatments like Finasteride, Minoxidil, and Nizoral, with evidence suggesting it enhances Minoxidil's effectiveness and can improve hair growth on its own. Users discuss various microneedling techniques, including heavy weekly sessions and lighter daily sessions, while expressing concerns about potential scalp damage and discomfort.

      community FINASTERIDE IS NOT FOR EVERYONE (like me), but you should still try it.

      in Chat  6 upvotes 5 years ago
      Exploring hair loss treatments, with a focus on Finasteride and RU58841 as well as other topical solutions like stemoxydine 5%. The user found that they were sensitive to both oral and topical finasteride, but remain optimistic about finding the right treatment.

      community 3yr Fin/Dut/Niz NW3+ —> NW1.5 Pictures with Writeup

      in Progress Pictures  32 upvotes 5 years ago
      A user improved their hair loss from NW3+ to NW1.5 over three years using a regimen of dutasteride, finasteride, Nizoral, biotin, and collagen. They experienced some side effects and adjusted dosages over time, and noted additional benefits like better skin and muscle gain.

      community Finasteride is saving me!!! 1 yr results

      in Progress Pictures  55 upvotes 9 months ago
      A 25-year-old male experienced significant hair regrowth after one year of using 0.5mg daily finasteride, with plans to add 1.25mg oral minoxidil and microneedling for further improvement. He also uses Nizoral shampoo weekly and reports no current side effects.
      What NW am I? Im guessing NW 1.5?

      community What NW am I? Im guessing NW 1.5?

      in General  57 upvotes 1 year ago
      The conversation is about a user assessing their hair loss as Norwood 1.5 and discussing their use of oral minoxidil and finasteride for 2.5 years, which improved their hair density. They are content with their current progress but hope to reach Norwood 1.

      community Verteporfin FUT 9 Month Update

      in Research/Science  79 upvotes 1 year ago
      Dr. Bloxham's 9-month update on FUT scar revision with Verteporfin shows promising results. Excitement is high for FUE, which appears highly effective based on Dr. Barghouthi's findings.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 5 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community Starting Fin soon. Wish me luck

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      A 19-year-old with NW2-2.5 hair loss is starting finasteride soon, considering low dosages of 0.25mg daily or 0.5mg 3-5 times a week. They are also using derma stamping, ketoconazole shampoo, ACV washes, and various oils to maintain hair quality and reduce scalp itch.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Green tea/ soy Isoflavones supplements for MPB

      in Product  4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.