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      community I am doing an experience with RU58841

      in Treatment 7 months ago
      The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.

      community NW3 > NW1: DUT and microneedling only

      in Progress Pictures  789 upvotes 4 years ago
      User Topher1999 achieved hair regrowth using Dutasteride 3 times a week and microneedling with Dr. Pen Ultima A6 every 2 weeks for 9 months. They believe microneedling is the main reason for hairline gains.

      community Green tea/ soy Isoflavones supplements for MPB

      in Product  4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

      community So... any chinese suppliers for real pyri?

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinical trials.

      community Gut health and hairloss are they linked!

      in Chat  7 upvotes 6 days ago
      Poor gut health may contribute to hair loss and scalp inflammation, with treatments like finasteride, minoxidil, and Nizoral being used. Improving gut health and addressing inflammation might help alleviate symptoms.

      community Are we still getting the PP405 phase 2a results by the end of March?

      in Research/Science  27 upvotes 1 month ago
      People are discussing the anticipated release of PP405 phase 2a results, expected by the end of March, with some skepticism about its effectiveness. There is cautious optimism due to past experiences with similar treatments like Breezula, despite concerns about the lack of presentation at the AAD 2026 conference.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 1 month ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community Breezula CB-03-01

      in Treatment  11 upvotes 6 years ago
      The conversation is about a potential new hair loss treatment called Breezula CB-03-01. Users are discussing updates on its development and sharing personal experiences with making or using it.

      community Anybody else lost a lot of gains on pyrilutamide?

      in Update  8 upvotes 3 years ago
      The conversation discusses hair loss and the ineffectiveness of a treatment called pyrilutamide, with one user experiencing negative results and questioning the product's authenticity.

      community Replicel Info - Possible Info Date

      in Update  12 upvotes 7 years ago
      Replicel's results were delayed, but Shiseido might share data at BioJapan on October 11. Users are hopeful for new treatments like RCH-01, potentially eliminating the need for finasteride or minoxidil.

      community Is this regrowth? ketoconazole

      in Is this regrowth?  13 upvotes 1 year ago
      The conversation is about hair regrowth treatments, including ketoconazole, vitamins, fish oil, collagen, pumpkin seed oil, rosemary, and dermal rolling. Users suggest trying finasteride and intense weight training to enhance results.

      community How promising is th RCH-01/Replicel treatment? Is there any new info that suggests it will be as successful as it claims? What other promising treatments are close?

      in Technology  12 upvotes 7 years ago
      The conversation is about the potential of the RCH-01/Replicel hair loss treatment and its lack of updates since 2013, with the user expressing hope for its success and considering using Minoxidil, finasteride, and dermarolling in the meantime. Other treatments mentioned as promising are Breezula and Tsuji.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 2 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community Aggressive diffuse thinning after 1 year of fin and min

      in Progress Pictures  7 upvotes 1 year ago
      The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Shiseido RCH-01

       5 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community Intermittent fasting reduces hair growth?!? :(

      in Research/Science  36 upvotes 1 year ago
      Intermittent fasting may inhibit hair growth by triggering a stress response that affects hair-follicle stem cells. Some users believe genetics and DHT play a larger role in hair loss, and treatments like Minoxidil and Finasteride are mentioned as ineffective for some.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 1 year ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community Any good experiences with Alfatradiol ?

      in Treatment  4 upvotes 5 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.