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      community Tretinoin & Minoxidil application

      in Chat  6 upvotes 2 years ago
      Using Tretinoin with Minoxidil may increase Minoxidil's absorption and improve hair growth results. The user is seeking advice on how to apply both treatments effectively.

      community What to add after dut/min/RU/needling?

      in Treatment  1 upvotes 2 years ago
      The conversation is about different treatments for hair loss, including minoxidil, finasteride, RU58841, and dermarolling. The conclusion is that RU58841 and dermarolling have shown efficacy in treating hair loss through different pathways.

      community Non responsive diffuse thinning

      in Progress Pictures  9 upvotes 9 months ago
      The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

      community For those that have used anti androgens what is your experience?

      in Research/Science  16 upvotes 2 years ago
      People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.

      community My protocol for combatting hair loss

      in Treatment  4 upvotes 4 years ago
      The conversation is about a hair loss treatment protocol involving microneedling, finasteride, RU58841, minoxidil, ketoconazole shampoo, and a scalp massager with oils. Some users advise starting with fewer treatments like finasteride, minoxidil, and microneedling to avoid potential side effects.

      community Status update on upcoming treatments

      in Technology  44 upvotes 6 months ago
      Current treatments for hair loss include finasteride, minoxidil, and derma rolling. New treatments like Breezula, PP405, and others are not expected until at least 2027 or later.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Pyrilutamide - your experience?

      in Product  12 upvotes 3 years ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 5 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community Questions about dutasteride, minoxidil and nuclear option?

      in Minoxidil  5 upvotes 4 years ago
      The user discussed their experience with hair loss treatments, including finasteride, RU58841, Nizoral, supplements, dermarolling, and minoxidil, which caused significant edema. They also experimented with dutasteride, which led to increased hair loss, and found that Armodafinil reduced minoxidil-related water retention and hair shedding.

      community MinoxiBoost - SULT1A1 Enzyme booster journey

      in Minoxidil  7 upvotes 2 years ago
      The user has tried topical Minoxidil and oral Minoxidil for beard and scalp hair growth with minimal results, and has been on Finasteride for 7 months with stabilized scalp hair but no facial hair improvement. They are considering using a SULT1A1 enzyme booster to enhance results and are questioning its effectiveness without concurrent topical Minoxidil application.

      community Steps before starting medication

      in Treatments  336 upvotes 5 months ago
      A 31-year-old man, between Norwood 4 and 5, is considering hair loss treatments like finasteride and minoxidil but is concerned about side effects. He is exploring options with doctors and considering a hair transplant, noting that some clinics require medication before and after the procedure.

      community Wanting to switch from topical to oral

      in Treatment  1 upvotes 1 month ago
      The user is considering switching from a topical hair loss treatment to oral medication. They currently use a topical solution with Minoxidil, Dutasteride, Finasteride, Tretinoin, and Ketoconazole and are seeking advice on transitioning to oral Dutasteride and Minoxidil.

      community Any supps/topicals you thought made a difference?

      in Product  4 upvotes 5 years ago
      The conversation discusses various hair loss treatments, with some users avoiding finasteride due to potential side effects and opting for alternatives like dermarolling, minoxidil, peppermint oil, and other natural remedies. Despite trying different supplements and oils, many users report limited success, with some eventually considering or using finasteride, dutasteride, or topical treatments for better results.

      community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community I'm becoming non-responder to minoxidil. What's going on?

      in Minoxidil  7 upvotes 10 months ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

      community Six (6) Months Update…Hope of more to come?

      in Progress Pictures  25 upvotes 1 year ago
      The user is disappointed with their hair loss progress after six months of using oral medications, laser therapy, microneedling, and vitamin D supplements. They are considering exosome therapy but are unsure of its effectiveness and are seeking advice on whether to continue or try other treatments.

      community Retinol substitute for Tretinoin

      in Minoxidil  4 upvotes 1 year ago
      The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.