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GlossaryImmunosuppressive Therapy

use of drugs to reduce immune system activity

Immunosuppressive Therapy, also known as Immunosuppression Therapy, involves the use of medications to reduce or suppress the activity of the body's immune system. This treatment is often used to prevent the rejection of transplanted organs, manage autoimmune diseases, and treat certain types of alopecia, where the immune system mistakenly attacks hair follicles.

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community Research and Question about Allopregnanolone, Multiple Sclerosis, TRT, and Finasteride

in Finasteride/Dutasteride 2 upvotes 3 years ago

A 52-year-old male with Multiple Sclerosis is considering using Finasteride and Testosterone Replacement Therapy (TRT) for hair loss but is advised to lose weight first to avoid side effects. He is currently focusing on diet, weight loss, and using Rogaine and microneedling for hair treatment.

community Starting Way-316606 for the first time today.

in Research/Science 30 upvotes 1 year ago

A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

community Does microneedling regrow hair on dormant bald regions which have been bald for many years?

in Microneedling 6 upvotes 6 years ago

Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 year ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community Microneedling aftercare advice

in Microneedling 4 upvotes 4 years ago

Microneedling aftercare involves using saline water instead of sea water, and avoiding hyaluronic acid due to its potential pro-inflammatory effects. Users suggest using jojoba oil as a carrier for essential oils like rosemary and lavender, and combining microneedling with minoxidil for better hair regrowth results.

community 22 yr asian male 2 year fin results

in Progress Pictures 135 upvotes 2 years ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 2 months ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

community Comparing the effect of T suppression and DHT suppression

in Transgender 52 upvotes 1 year ago

Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.

community Pyrilutamide cease and desist from Kintor

in Transplants 12 upvotes 3 years ago

Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

community Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity

in Minoxidil 1 upvotes 1 year ago

Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.

community Comparing the effect of T suppression and DHT suppression

in Transgender 89 upvotes 1 year ago

The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

community Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?

in Treatment 3 upvotes 2 years ago

The conversation is about adding crushed bicalutamide or spironolactone to a topical mix with finasteride and minoxidil to suppress testosterone in hair follicles, similar to what RU58841 does. The user cannot obtain RU58841 in their country and is seeking advice on this alternative approach for hair loss treatment.

community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?

in Research/Science 4 upvotes 3 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Estradiol mesotherapy / idea feedback

in Female 6 upvotes 1 year ago

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

community Anyone try a combo therapy of everything except fin? Minox + Tret + microneedling + caffeine, etc

in Chat 1 upvotes 1 year ago

The user experienced severe side effects from finasteride and is considering a combination therapy including Minoxidil, Tretinoin, microneedling, caffeine, and other ingredients. They are also thinking about adding red light therapy and microneedling once per week.

community Been on treatment for two months.

in Is this regrowth? 9 upvotes 6 months ago

The user is using ketoconazole shampoo, 5% minoxidil, and microneedling for hair loss treatment. It's suggested that adding a DHT suppressant like finasteride could improve results.

community Temple recession continues, 19 MtF, Monotherapy w/ confirmed low T, also taking 1.25mg Finasteride,

in Transgender 115 upvotes 7 months ago

A 19-year-old transgender individual is experiencing worsening temple recession despite taking female hormones and 1.25mg finasteride. They are seeking advice on additional treatments to address hair loss.

community How can this be? I'm on a damn MTF regimen and still getting decimated

in Transgender 1 year ago

The conversation is about a person using minoxidil, finasteride, estrogen, and bicalutamide to combat hair loss, expressing frustration and desperation over their situation. They are advised against using female hormones and encouraged to focus on finasteride and minoxidil, with suggestions to seek therapy for mental health support.

community concentration of my finasteride therapy

in Finasteride/Dutasteride 4 upvotes 10 months ago

The conversation discusses a topical finasteride therapy with hydrocortisone butyrate, estrone base, and breviline. A user suggests oral finasteride as a superior option.

community Insane MTF recovery 18 months blocking androgens

in Progress Pictures 145 upvotes 3 years ago

Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.

community TRT. Pyrilutamide. Ru58841. Help

in Treatment 3 upvotes 2 years ago

A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

community Pyrilutamide or RU Monotherapy?

in Treatment 6 upvotes 3 years ago

Using Pyrilutamide or RU as monotherapy for hair loss? Share experiences.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 2 years ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community Low dose spiro with 5ARI inhibitor

in Chat 2 upvotes 1 year ago

Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 5 upvotes 1 year ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community HT booked, taking finasteride and losing ground?

in I'm Starting Treatment 1 upvotes 3 months ago

The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

community im gonna nuke and destroy DHT :angry_emoji: 😡😡😡😡👌

in Finasteride/Dutasteride 1 year ago

A 16-year-old is experiencing hair loss and is using minoxidil, finasteride, and plans to add RU58841, while considering other treatments like MK-677 and microneedling. Concerns are raised about the potential impact of these treatments on puberty and development.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 2 years ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 1 year ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.