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GlossaryImmunosuppression

reduction of immune system activity or effectiveness

Immunosuppression, also known as immune suppression, refers to the reduction of the activation or efficacy of the immune system. This can be a deliberate process, such as when medications are used to prevent the body from rejecting a transplanted organ, or it can occur as a side effect of treatments like chemotherapy. It can also result from certain diseases that inherently weaken the immune response.

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community Starting Way-316606 for the first time today.

in Research/Science 30 upvotes 1 year ago

A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

community Research and Question about Allopregnanolone, Multiple Sclerosis, TRT, and Finasteride

in Finasteride/Dutasteride 2 upvotes 3 years ago

A 52-year-old male with Multiple Sclerosis is considering using Finasteride and Testosterone Replacement Therapy (TRT) for hair loss but is advised to lose weight first to avoid side effects. He is currently focusing on diet, weight loss, and using Rogaine and microneedling for hair treatment.

community Microneedling aftercare advice

in Microneedling 4 upvotes 4 years ago

Microneedling aftercare involves using saline water instead of sea water, and avoiding hyaluronic acid due to its potential pro-inflammatory effects. Users suggest using jojoba oil as a carrier for essential oils like rosemary and lavender, and combining microneedling with minoxidil for better hair regrowth results.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 year ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community Does microneedling regrow hair on dormant bald regions which have been bald for many years?

in Microneedling 6 upvotes 6 years ago

Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.

community Dutasteride has been nuking me

in Finasteride/Dutasteride 156 upvotes 5 months ago

The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.

community 22 yr asian male 2 year fin results

in Progress Pictures 135 upvotes 2 years ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

community Treating my DUPA via controlling inflammation

in Treatment 5 upvotes 2 years ago

The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

community The DEFINITIVE cure for hairloss

in Satire 270 upvotes 10 months ago

The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 1 week ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?

in Research/Science 4 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Betamethasone dipropionate 0.05 (sernivo spray)

in General 76 upvotes 1 year ago

A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 11 months ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community Depressed that DUPA rules me out of a transplant

in Chat 8 upvotes 2 years ago

A user is upset about hair loss due to seborrheic dermatitis and DUPA, which prevents a hair transplant. They mention using jojoba oil and discuss treatments like Minoxidil, finasteride, and RU58841.

community can someone help me identify these pls

in Treatment 5 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Is it possible to transplant mice skin into human body?

in Transplants 47 upvotes 6 months ago

Transplanting mice skin to humans is not feasible due to immune rejection, but some suggest genetic modification or immune suppression could make it possible. Xenograft hair transplants are discouraged.

community Hair transplant histamine issues (could be antibiotics taken during transplant!?)

in Transplants 1 upvotes 2 years ago

User experienced severe allergic reactions and liver issues after a hair transplant, likely due to antibiotics and medications. Despite trying Minoxidil, the user faced further complications and is now seeking medical advice for potential future transplants.

community 6 years post transplant.. NO meds

in Transplants 779 upvotes 2 years ago

User had a hair transplant in 2016 but stopped taking finasteride due to side effect concerns. Now considering another transplant and starting finasteride, minoxidil, and microneedling to improve hair situation.

community Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?

in Finasteride 4 upvotes 7 years ago

The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.

community Lilly to seek first approval of an autoimmune drug for hair loss

in Research/Science 19 upvotes 4 years ago

Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 1 year ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?

in Treatment 3 upvotes 2 years ago

The conversation is about adding crushed bicalutamide or spironolactone to a topical mix with finasteride and minoxidil to suppress testosterone in hair follicles, similar to what RU58841 does. The user cannot obtain RU58841 in their country and is seeking advice on this alternative approach for hair loss treatment.

community Diagnosed with a mild form of Alopecia

in Treatment 5 years ago

A user experienced rapid hair loss and was prescribed Desonide cream for mild Alopecia. They are seeking feedback on its effectiveness and potential side effects.

community “15 week progress on aggressive protocol (dut + min + microneedling) — am I on track for transplant candidacy?

in Progress Pictures 10 upvotes 1 month ago

The user has been using a hair loss treatment protocol including topical dutasteride, minoxidil with tretinoin, ketoconazole shampoo, microneedling, a laser cap, and vitamin D for 15 weeks, showing impressive progress. Feedback suggests continuing medical therapy for 12-24 months before considering a hair transplant.

community Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity

in Minoxidil 1 upvotes 1 year ago

Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.

community Is it okay to simultaneously use Min and Betamethasone?

in Minoxidil 2 years ago

A user with seborrheic dermatitis uses Ketoconazole 2% and Betamethasone and is considering starting Minoxidil for thinning hair. They are concerned about using Minoxidil and Betamethasone simultaneously.

community Olumiant alternative for Alopecia Areata?

in Treatment 1 upvotes 3 years ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 4 upvotes 1 year ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.