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      community Curious about 'nuclear' stacks

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

      community Pyrilutamide update number 1 - 1 week use

      in Update  55 upvotes 3 years ago
      A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

      community Seeking Advice After Frustrating Dermatologist Visits: Min/Fin vs Supplements

      in General  119 upvotes 9 months ago
      The user is frustrated with dermatologists who dismiss Minoxidil and finasteride as unsafe, instead recommending mustard oil, PRP, zinc supplements, and hair products. The user feels these suggestions are ineffective and is considering starting Minoxidil and finasteride despite the dermatologists' advice.

      community Figuring out my own experimental protocol

      in Treatment  11 upvotes 3 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 8 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community Nest topical compound stack to fight hair loss

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

      community DNA Test for better suited treatment?

      in Treatment  3 upvotes 8 months ago
      The conversation is about hair loss treatments, specifically discussing the use of dutasteride, minoxidil, and the potential benefits of a DNA test and PRP therapy. Opinions vary, with some users skeptical about the DNA test and PRP, suggesting sticking with current treatments.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community Possibilities without Fin/Dut ?

      in Treatment  4 upvotes 3 months ago
      The user experiences severe side effects from finasteride and dutasteride, including low libido and anxiety, and is currently using oral minoxidil despite shortness of breath. They are seeking alternative treatments for hair loss, having tried pyrilutamide, fluridil, and RU58841 with no success, and are considering future treatments or a hair transplant.

      community Diffuse thinning fucking sucks

      in Update  430 upvotes 2 years ago
      The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Are these all the anti androgen products?

      in Treatment  6 upvotes 2 years ago
      The conversation lists hair loss treatments including finasteride, dutasteride, RU58841, pyrilutamide, breezula, and fluridil, and suggests ketoconazole as another option. Some users warn against using certain treatments like cyproterone acetate, bicalutamide, and spironolactone due to their strong anti-androgen effects and potential impact on masculinity.

      community Pyrilutamide for non-5AR users?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

      community How’s RCH-01 doing?

      in Treatment  6 upvotes 6 years ago
      RCH-01's progress is uncertain, and there's skepticism about its effectiveness. Users are losing hope in this treatment.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  128 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Epibiotech Hair Multiplication

      in Technology  16 upvotes 5 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also references Epibiotech's hair multiplication and cell therapy as potential solutions.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Dut mesotherapy shed or not working

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced initial success with topical minoxidil and dutasteride mesotherapy but is now losing more hair and unsure if it's due to shedding or ineffective treatment. They are considering whether to try a different approach.