Androgenetic alopecia is caused by DHT affecting hairgrowth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hairgrowth.
Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hairgrowth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.
A user started taking finasteride due to increasedhair shedding and sought advice on coping with the anxiety of starting the treatment. Responses included personal experiences with finasteride, minoxidil, and tips for integrating the medication into daily routines.
A user shared their 2-month hairgrowth progress using only Minoxidil, noting significant improvement and plans to continue despite a genetic predisposition to baldness. They apply Minoxidil twice daily, experienced a heat rash, and chose not to use Finasteride due to side effects.
Hair loss treatments like GT20029, pyrilutamide, and Follica show promise in 2022. Phase 1 and 2 trials are underway, and new hairgrowth studies have been published.
A 32-year-old has seen positive hairgrowth after 4.5 months using 0.5mg daily of oral dutasteride and 5mg of oral minoxidil, despite previously losing hair due to stopping medications and wearing a hair system. They plan to continue treatment and are considering adding dermarolling to their regimen, with a hair transplant scheduled for the following year.
Minoxidil and finasteride work through different mechanisms; minoxidil-dependent hair requires continued use to maintain growth, while finasteride prevents further hair loss but cannot sustain minoxidil gains alone. Current treatments like minoxidil, finasteride, and others need indefinite use, as no permanent solution exists yet.
The user increased their dutasteride dose from 0.5mg to 3mg daily to address hair thinning, noticing a change in shedding patterns and possibly thicker hair. Other users discuss the effectiveness of different dutasteride doses on DHT levels and suggest staying consistent with the treatment.
Rotenone, a natural plant extract, may promote hairgrowth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.
Low vitamin D levels can negatively impact hairgrowth, and supplementing with vitamin D, along with treatments like finasteride and minoxidil, may help improve hair health. Quitting smoking and ensuring adequate vitamin B12 and K2 intake are also suggested to support hair regrowth.
Switching from finasteride to dutasteride can initially increasehair shedding, but some users eventually see improvement. Experiences differ, with some finding dutasteride more effective, while others face worsening hair loss or side effects.
A 19-year-old using topical minoxidil and dutasteride reports significant hairgrowth and shedding. Minoxidil caused new facial hairgrowth, and the user hopes for thicker hair regrowth.
A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.
Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.
The conclusion of the conversation is that the user, "Hello_Knicks," achieved significant hairgrowth and density by consistently using a combination of finasteride, dutasteride, minoxidil, dermarolling, nizoral, vitamin supplements, and a healthier diet. The user, who is a medical doctor, believes that patience, persistence, and medication compliance are key factors in achieving positive results.
Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hairgrowth.
Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.
Creatine is reported by many to increasehair loss, though no scientific evidence supports this. Some use finasteride and minoxidil to manage hair loss, while others avoid creatine due to personal experiences.
The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.
Mooseman1944 noticed hair regrowth and less shedding during the first 6 months of taking finasteride, but is now experiencing increased shedding and thinning hair. They are considering switching to dutasteride or adding minoxidil if there's no improvement by next August.
User experienced 100% testosterone increase after using Finasteride and Dutasteride for hair loss. Some users discuss potential side effects and reasons for the increase.
Whether topical caffeine can be as effective for hairgrowth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.
Oral minoxidil and finasteride effectively improved hairgrowth and stopped hair loss, with no major side effects. The user switched from topical to oral minoxidil, added finasteride, and later transitioned to dutasteride, experiencing regrowth and thicker hair.
User started minoxidil and microneedling for hairgrowth and saw amazing results, but recently experienced hair thinning again. Others suggest adding finasteride, but user is hesitant and has difficulty obtaining it.
The user stabilized hair loss with oral Finasteride and saw significant hairgrowth after adding oral Minoxidil. They also used collagen peptides and had no side effects.
Topical dutasteride 0.05% is more effective for hairgrowth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.
Minoxidil and dermarolling can yield positive hairgrowth results, but long-term effectiveness varies, and some users experience hair loss again without additional treatments like finasteride. Microneedling enhances minoxidil's effectiveness by increasing enzyme activity, but individual experiences differ.
Microneedling is often combined with minoxidil for hairgrowth, but concerns about scalp damage, pain, and effectiveness deter some users. Alternatives like finasteride, dutasteride, tretinoin, and laser treatments are preferred by others.
Microneedling is still considered effective for hairgrowth, especially when combined with minoxidil, though it is time-consuming. Some users report significant success with consistent use, while others find it less popular due to the effort required compared to topical treatments alone.
The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.