Lab-grown hair using iPSCs is being explored, but practical applications are limited. Finasteride is suggested as the only current effective treatment.
A young woman, 23, is experiencing all-over hair thinning and has been using Minoxidil 5% foam, iron supplements, and vitamin D with no improvement. She feels depressed and is seeking support and advice on what to try next.
Stem-cell hair transplants could potentially create thousands of grafts from a single donor graft, offering a solution for hair loss with DHT-resistant hair. Companies like Stemson Therapeutics and OrganTech are working on this technology, which may become available in the future, possibly reducing the cost and making it widely accessible.
The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.
PP405 shows promise in hair loss treatment, but stemcell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stemcell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.
The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.
A user is losing hope after 5 months on finasteride, seeing more hair loss and minimal positive changes. Another user advises that shedding is normal and benefits may take up to 2 years.
PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.
PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stemcell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.
Stemson Therapeutics will start human trials for hair cloning in late 2025-2026. Product development is complete, and they are preparing for production and clinical trials.
Stemson Therapeutics announced a breakthrough in hair growth technology using stem cells. Users discussed the potential high cost and skepticism about the treatment's accessibility.
PP405 shows promise for hair regrowth by manipulating stemcell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.
The conversation discusses the progress and potential of hair cloning by Stemson Therapeutics, questioning if it will be realized in the next 5-10 years or if it's just false hope. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
Stemcell treatments for hair restoration can be effective, but results vary and depend on factors like the type of stem cells used and timing of treatment. PRP and exosomes have shown some success, while costs and effectiveness differ by location, with South Korea and Turkey offering more affordable options.
The user is experiencing severe hair shedding while on finasteride and plans to start using ketoconazole shampoo to address a greasy, waxy scalp buildup. They are seeking additional advice for managing hair loss.
A user shared their 2-year results using only 0.5mg finasteride for hair loss, noting improvement after 8-10 months and no major shedding or side effects. They are 34 years old and have avoided using Minoxidil.
A 22-year-old male is experiencing a significant hair shed and a receding hairline despite being on finasteride for 14 months and minoxidil for 7 months, applied inconsistently on the temples. He is considering adding dutasteride to his regimen once a week.
The post discusses the theory that melatonin could reverse grey hair by regulating certain enzymes. However, users who have taken melatonin reported no effect on preventing or reversing grey hair.
Using a 1mm derma roller every day with nanoxidil is not recommended; it should be used once a week. The user had no initial instructions and used it nightly for two months.
The conversation discusses hair loss treatments, specifically comparing rosemary and Redensyl, with the original poster already using finasteride and minoxidil. Users also mention using topical melatonin, caffeine, geranium, rosemary oil, jojoba, coconut, and argan oil for hair and scalp care.
A 24-year-old male experienced an increase in estradiol levels and symptoms like gynecomastia and excessive sweating after using Minoxidil for hair loss. His estradiol levels decreased after he stopped using Minoxidil.