Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.
Individuals with oily scalps, dandruff, and diffuse thinning hair loss who have managed to either halt the loss or regrow their hair by using topical finasteride and minoxidil as well as microneedling and ketoconazole 2% shampoo.
A user's 3-month progress with a combination of finasteride, minoxidil and dermarolling for hair loss; other users shared their experiences and advice.
The user experienced hair thinning from chromium and alpha lipoic acid supplements, which stopped after discontinuing them. Someone mentioned this could be telogen effluvium, a temporary condition.
The user is experiencing hair loss, possibly due to androgenetic alopecia and seborrheic dermatitis, and has tried ketoconazole shampoo without success. They are hesitant to use finasteride due to potential side effects and are seeking advice on managing their condition.
User tried topical fin, dut, min, tret, hydrocortisone, microneedling, nizoral, collagen, propidren supplements, and laser helmet for hair loss with slow progress. They ask if topical spironolactone is a safer, effective alternative to RU for suppressing testosterone and treating hair loss in men.
Topical dutasteride residue on pillows may cause ear redness and irritation. The user is concerned about a contact reaction from the treatment transferring to the pillow.
The conversation discusses a user's experiment with using hot water and a dermastamp to reduce hair loss, improve dandruff, and promote new hair growth. The user advises caution and mentions not sharing photos until more progress is visible.
The conversation is about a topical spray containing finasteride, minoxidil, and tretinoin, with users discussing its effectiveness compared to more established brands. One user mentions using a product with 5% minoxidil, 0.15% finasteride, and 0.15% tretinoin.
Reducing sugar intake may lessen scalp itchiness associated with hair loss, even when using treatments like finasteride. Some users also report similar symptoms while on dutasteride.
Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.
People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.
The user plans to use a combination of tretinoin, topical minoxidil, and topical finasteride for hair loss treatment. They seek advice on application order, timing, and tretinoin dosage.
Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.
RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
The conversation is about managing seborrheic dermatitis and hair loss using treatments like Nizoral, Kelual DS, KPL, and MCT oil daily. The user is concerned about the effectiveness and safety of using MCT oil every day.
Finasteride effectively treated hormonal acne for multiple users, including the original poster. Topical treatments like Winlevi are effective but expensive and not always covered by insurance.
A 19-year-old concerned about long-term effects of 5AR inhibitors on physical appearance. They have used finasteride and plan to try dutasteride or RU58841; responses suggest improved skin, hair, and confidence.
Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.
A 22-year-old experiencing hair loss and persistent scalp itchiness since age 16 has tried various treatments, including finasteride, ketoconazole shampoo, and dietary changes, with no success. Suggestions include consulting a knowledgeable dermatologist, considering seborrheic dermatitis, and trying different shampoos like Selsun Blue or those with selenium sulfide.
An 18-year-old is frustrated with a dermatologist who prescribed shampoos and Betnovate instead of Minoxidil and Finasteride for hair loss and seborrheic dermatitis. The user feels misled and is considering giving up on dermatologists.
The user shared their 3.5-month progress using topical minoxidil, ketoconazole shampoo, and dermarolling for hair loss, and plans to start finasteride. They experienced relief from scalp issues with ketoconazole and are managing side effects from minoxidil.
Kintor apologized for using misleading images in their advertisements and promised stricter review processes. They are also considering developing a topical dutasteride formulation.
The user experienced hair loss after switching to daily microneedling and stopping tretinoin, while continuing oral finasteride, minoxidil, and other treatments. The consensus suggests daily microneedling is excessive and harmful, recommending less frequent sessions to allow healing.
Topical spironolactone is discussed for hair loss treatment, with mentions of DIY solutions and dermatologist compounding. Users inquire about regrowth and sourcing the treatment.
Finasteride can cause oily skin and acne due to increased testosterone or sensitivity of androgen receptors. Some users find dutasteride results in less oily skin compared to finasteride.
The user is experiencing an itchy scalp after six months of using dutasteride and minoxidil, suspecting dutasteride as the cause. They are seeking advice on how to alleviate the itch without stopping the treatment.