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      community Brainstorming: upping your dermarolling game

      in Research/Science  5 upvotes 2 years ago
      The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

      community PP405 Effectiveness in Transplant Area?

      in Transplants  3 upvotes 5 months ago
      Hair transplant recipients are concerned about whether dormant follicles are permanently damaged by incisions, but some believe undamaged follicles could still regrow if a treatment like PP405 is effective. Opinions vary on the impact of transplants on original follicles, with some suggesting treatments like finasteride can help regrow hair.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  13 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community High Dose Niacin Update

      in Update  5 upvotes 8 years ago
      High dose niacin (1000mg daily) seems to have halted hair loss but did not regrow lost hair. The user plans to continue due to additional benefits like lower stress and higher good cholesterol.

      community Epibiotech Hair Multiplication

      in Technology  16 upvotes 5 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also references Epibiotech's hair multiplication and cell therapy as potential solutions.

      community 1600 grafts (~5500 hairs) | 10 month results

      in Transplants  1669 upvotes 11 months ago
      The user received 1600 hair grafts but is dissatisfied and plans a second transplant for better coverage. They use minoxidil and finasteride and are considering adding dutasteride.

      community My Estradiol Level on Finasteride

      in Research/Science  17 upvotes 1 year ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  60 upvotes 2 years ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community HMI-115 when will it be available

      in Research/Science  15 upvotes 3 years ago
      The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Do I enjoy microneedling too much?

      in Satire  26 upvotes 10 months ago
      The conversation is about the use of microneedling, specifically with a derma stamp, for hair regrowth. Users discuss their experiences, pain levels, and the satisfaction of taking control over hair loss, with some mentioning the use of Minoxidil to enhance results.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 2 years ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 1 year ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community 10 weeks on 0.25mg fin daily + collagen + biotin supps

      in Progress Pictures  30 upvotes 1 year ago
      User experienced hair regrowth and no side effects after 10 weeks on 0.25mg finasteride daily, along with biotin, collagen, micro-needling, and hair oil. They stopped minoxidil due to inconvenience and noticed initial shedding but now see more fullness.

      community Extreme growth from only vitamins!

      in Update  63 upvotes 1 year ago
      A user experienced significant hair regrowth after improving their diet, getting sunlight, taking a multivitamin, and exercising, following a period of extreme calorie restriction and hair shedding. Others in the conversation attribute the hair regrowth to increased calorie intake rather than just vitamins.

      community AGA responded to steroid shots? Biopsy wrong? Please help!

      in Female  2 upvotes 2 years ago
      A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 5 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.