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    GlossaryInterferons

    Interferons are a group of signaling proteins produced by the immune system in response to viral infections and other stimuli. They play a crucial role in regulating immune responses and have been studied for their potential effects on hair biology, particularly in conditions like alopecia areata, where they may help modulate inflammation and promote hair regrowth. Key distinguishing characteristics of interferons include their ability to enhance the activity of immune cells and their role in inhibiting viral replication, which can indirectly influence hair follicle health and cycling.

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      community Combining topicals together or use them separately

      in Chat  4 upvotes 9 months ago
      Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  44 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 1 year ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community Could coffee contribute to hair loss?

      in Research/Science  4 upvotes 4 years ago
      Coffee may negatively impact hair health due to its vasoconstrictor effects, potential to increase DHT, and interference with nutrient absorption. There is no strong clinical evidence linking caffeine to hair loss or regrowth in humans, but moderation is advised.

      community Ru 58841 and essential oils question

      in Treatment  3 upvotes 4 years ago
      The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.

      community How to deal with mpb stress at an young age, Please help

      in Chat  6 upvotes 2 months ago
      A 17-year-old is stressed about mild male pattern baldness and is considering treatments like minoxidil and finasteride but is concerned about starting finasteride too young. Users suggest starting with minoxidil and considering finasteride at 18, while emphasizing the importance of consulting a doctor and not obsessing over hair loss.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Combining all your topicals into one

      in Treatment  3 upvotes 2 years ago
      The user is using a hair loss treatment regimen that includes applying various topical solutions and taking oral medication. They are mixing their topical treatments to save time but are concerned about the effectiveness of the treatments when combined and stored.

      community Gut health and hairloss are they linked!

      in Chat  7 upvotes 2 months ago
      Poor gut health may contribute to hair loss and scalp inflammation, with treatments like finasteride, minoxidil, and Nizoral being used. Improving gut health and addressing inflammation might help alleviate symptoms.

      community Take the meds, but know that LIFESTYLE MATTERS

      in Research/Science  20 upvotes 2 months ago
      Minoxidil and finasteride aid hair regrowth, but a healthy lifestyle, including proper nutrition and maintaining a healthy weight, enhances their effectiveness. Being underweight can impede hair regrowth, while a balanced diet and addressing deficiencies can improve outcomes.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 7 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
      Seeking Advice After FUT Hair Transplant in 2021 – Considering FUE

      community Seeking Advice After FUT Hair Transplant in 2021 – Considering FUE

      in General  92 upvotes 11 months ago
      The user is unhappy with the results of a FUT hair transplant from 2021, noting uneven hair texture and persistent thinning. They are considering a FUE procedure and have been using finasteride for a year, previously used minoxidil, and currently use Toppik for concealment.

      community From Balding Crown to Full Coverage – My Real Progress with a Combined Protocol (But One Big Question About the Hairline)

      in Progress Pictures  101 upvotes 1 year ago
      The user shared their successful hair regrowth using oral finasteride, minoxidil foam, a custom topical solution, ketoconazole shampoo, and microneedling, resulting in significant improvement at the crown. However, they experienced hairline recession after switching to a topical solution with finasteride and minoxidil, raising concerns about its effectiveness.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community 3 Month Progress - Topical Fin & Min

      in Progress Pictures  623 upvotes 1 year ago
      A 24-year-old user shared their 3-month progress using a topical spray containing 0.3% finasteride and 6% minoxidil, along with dermarolling and Nizoral shampoo, reporting reduced shedding and signs of hair regrowth. They emphasized consistency in their routine and noted no side effects, expressing optimism about future results.

      community Thank you guys! Before this sub I thought all hair-grow-back product are scam.

      in Minoxidil  642 upvotes 1 year ago
      A user shared their positive experience with hair regrowth using Finasteride and Minoxidil, noting increased confidence and no serious side effects except for increased body hair. Others in the conversation discussed varying results, potential side effects, and the possibility of switching to Dutasteride if effectiveness decreases.