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GlossaryInterleukin-7

protein crucial for T cell development and hair follicle maintenance

Interleukin-7 (IL-7) is a protein that plays a crucial role in the immune system by promoting the development and survival of T cells, which are essential for the body's defense against infections. It is also involved in the maintenance of hair follicles, and disruptions in IL-7 signaling can be linked to conditions like alopecia, where hair loss occurs due to immune system imbalances.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 5 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?

in Research/Science 4 upvotes 3 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community IGF-1 and Peptides? Miracle molecule waiting to be found

in Research/Science 10 upvotes 9 months ago

The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 9 upvotes 5 months ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community Thoughts on Lactobacillus Reuteri 6475?

in Treatment 3 upvotes 1 year ago

Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 2 years ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community Signs of life. Ru, topical fin/min, mk677, micro needling

in Progress Pictures 192 upvotes 4 years ago

The conversation discusses using RU58841, topical finasteride/minoxidil, MK677, and microneedling as treatments for hair loss. MK677 is mentioned as a growth hormone that improves hair health and recovery from microneedling.

community MCL1 does anyone knows anthying about it

in Research/Science 9 upvotes 1 year ago

MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

community The story of RU58841/PSK3841

in Research/Science 1 year ago

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 2 years ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community PP405 - hair stem cell stimulation

in Research/Science 53 upvotes 2 years ago

PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

community Molecular mechanisms triggered by Micronedlling -- Intersting Publication to better understand Dermarolling

24 upvotes 7 years ago

This post and conversation are about the molecular mechanisms triggered by microneedling, specifically its effects on inflammation, tissue remodeling, epithelial proliferation, differentiation, and collagen synthesis. The discussion highlights the potential benefits of microneedling for hair loss treatment.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community Xeljanz....the magic drug!!!

2 upvotes 7 years ago

A user experienced significant hair regrowth from Xeljanz after severe alopecia but can no longer afford it. They are seeking ways to obtain the medication despite its high cost and potential side effects.

community 7 Month Update – Daily Topical Fin/Min, Weekly Microneedling (40)

in Progress Pictures 172 upvotes 3 years ago

A 7-month update of hair regrowth achieved by using daily topical finasteride and minoxidil, combined with weekly microneedling. It is also noted that the results are different for females.

community Lyphar Biotech. China source for RU58841

in Research/Science 1 upvotes 4 months ago

The conversation discusses the safety and trustworthiness of ordering RU58841 from Lyphar Biotech in China, with a focus on pricing and reliability. The user is seeking advice on whether to proceed with the purchase or consider alternative sources.

community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

in Research/Science 4 upvotes 2 years ago

The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

community Any point in microneedling with RU?

in Microneedling 1 upvotes 9 months ago

Microneedling with RU58841 may not be necessary since RU works topically by occupying receptors before DHT binds. RU58841 is a topical anti-androgen.

community ASCEplus HRLV Exosomes with microneedling

in Product 1 upvotes 2 years ago

The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

community COQ10 + PQQ for scalp inflammation??

in Chat 6 upvotes 2 years ago

A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.

community 7 month on Finesteride 1mg. Regrowth or not?

in Is this regrowth? 2 upvotes 11 months ago

The user has been using Finasteride for seven months to address hair loss but hasn't seen noticeable regrowth and is experiencing brittle, thinning hair with scalp issues. They are also using Salisia and Re’equil Salicylic Acid shampoo for potential psoriasis and are seeking advice from others with similar experiences.

community Ru58841 stops seb derm ( the itching)?

in Treatment 8 upvotes 2 years ago

RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.

community 7 month progress Min/Fin/Microneedle/Ketoconazole

in Progress Pictures 11 upvotes 2 years ago

The user has been treating hair loss for 7 months using a combination of pyrilutamide, a topical mix of finasteride and minoxidil, microneedling, a topical mix of GHK-Cu and minoxidil, ketoconazole shampoo, fish collagen peptides, zinc, and vitamin D3. Another user suggests that continuous small improvements could lead to significant hair regrowth over time.

community Ru58841 completely got rid of my seb derm

in Chat 7 upvotes 2 years ago

RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.

community Fin/dut increase in estrogen and autoimmune diseases

in Chat 7 upvotes 3 years ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community 7 months finally some real progress – fin min microneedling pyril

in Progress Pictures 17 upvotes 3 years ago

Hair loss treatment progress after 7 months using a combination of finasteride, minoxidil, microneedling and pyrithione zinc.

community 7 month fin and min young diffuse thinner update

in Progress Pictures 96 upvotes 2 years ago

A user shared a 7-month update on hair regrowth using finasteride daily and minoxidil once a day, noting improvement in hair health. Others suggested adding micro-needling, ketoconazole shampoo, and considering a hair transplant for better results.

community I think Ru58841 stopped my itching.

in Chat 4 upvotes 1 year ago

RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.