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      community Dutasteride for trans men? (Topical vs oral?)

      in Transgender 1 year ago
      The conversation discusses using dutasteride, both topical and oral, for hair loss in trans men, considering potential side effects like depression and libido issues. The user is exploring options including topical solutions with minoxidil, retinoic acid, and hydrocortisone, and plans to start microneedling.

      community Has anyone got results from pyrilutamide?

      in Research/Science  3 upvotes 4 months ago
      The user maintained hair with minoxidil, alfatradiol, and fluridil after stopping finasteride due to erectile dysfunction. They recently added pyrilutamide and are seeking feedback on its effectiveness after six months of use.

      community Starting Propecia with pre-existing erecticle dysfunction

      in Finasteride  5 upvotes 8 years ago
      A 19-year-old with diffuse hair thinning and erectile dysfunction is considering starting Propecia (finasteride) while already using a minoxidil solution with anti-androgens. Concerns are raised about the psychological nature of erectile dysfunction and the potential systemic effects of anti-androgens, with suggestions to address porn addiction and consult a doctor about hormone therapy.

      community Treatments to maintain alternative to finasteride/dutasteride

      in Treatment  6 upvotes 4 years ago
      A 29-year-old male experiencing hair loss due to TRT is using minoxidil and dermarolling but is hesitant to use finasteride or dutasteride due to potential side effects. He is considering low level laser therapy (LLLT), PRP, ketoconazole shampoo, and oral minoxidil as additional treatments. A reply suggests that without a DHT blocker like finasteride or dutasteride, other treatments may not be effective long-term.

      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 1 year ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community Topical fin and min and swallowing semen

      in Finasteride/Dutasteride  118 upvotes 1 year ago
      A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

      community Finasteride + Cialis together long term?

      in Treatment  3 upvotes 1 year ago
      The user has been on 1mg finasteride for a year, experiencing low libido and moderate erectile issues. They are considering using Cialis daily with finasteride long term to address these side effects.

      community M30, month 4 of dutasteride and minoxidil

      in Progress Pictures  125 upvotes 7 months ago
      A 30-year-old male is using dutasteride, minoxidil, ketoconazole shampoo, and various supplements for hair loss, reporting no sexual side effects but experiencing tinnitus. He stopped microneedling and tretinoin cream, saw quick results, and experiences low-intensity shedding.

      community Throwing Fluridil (Eucapil) into the mix.

      in Product  6 upvotes 5 years ago
      A user named "tresslessinseattle" receiving a mysterious package of Eucapil hair loss treatment, which they are considering in combination with Minoxidil and Finasteride treatments to boost the regrowth they have been seeing.

      community Topical fin working when oral has failed?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user switched from oral finasteride to dutasteride with minoxidil, but saw no results. They then tried topical finasteride and noticed some potential improvement after four months, theorizing that the topical application bypasses liver metabolism.

      community ABS-201 Trial - What should I know going in

      in Research/Science  26 upvotes 1 month ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

      community Tropoelastin injections + verteporfin?

      in Research/Science  12 upvotes 3 years ago
      The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

      community 3 months on Finasteride-Minoxidil-Microneedling 36M

      in Is this regrowth?  2 upvotes 1 month ago
      A 36-year-old male has been using finasteride, 5% minoxidil foam, and microneedling with a 0.75mm dermastamp or Dr. pen for three months. He notices thicker hair and reduced hair loss, with high testosterone and normal DHT levels, while managing prolactin levels with vitamin B6.

      community Testicular pain/discomfort....how long will this last? (29/m)

      in Question  4 upvotes 8 years ago
      A user experienced testicular pain after taking finasteride for hair loss and considered lowering the dose to 0.25mg to manage side effects. They also considered adding minoxidil to their routine while seeking advice on whether to continue or stop finasteride.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 3 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Needling project, I'm needling half of my head

      in Microneedling  1 upvotes 1 year ago
      A person is experimenting with microneedling on one temple while using Minoxidil to address hair loss. They plan to needle weekly and apply Minoxidil twice daily, avoiding application around needling sessions.

      community Dutasteride Mesotherapy or Oral Finasteride

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      A user is considering dutasteride mesotherapy versus oral finasteride for hair loss, with concerns about side effects. Other users share experiences with both treatments, suggesting oral finasteride as more effective and cost-efficient, while also discussing the use of minoxidil, alfatradiol, and potential side effects like gynecomastia.

      community How to correctly dose Saw Palmetto and Pumpkin Seed Oil

      in Research/Science  5 upvotes 1 year ago
      The user takes 1 mg finasteride three times a week, topical minoxidil daily, and Saw Palmetto both topically and orally on non-finasteride days. They recently added 1 g of pumpkin seed oil daily to improve hair thickness and are seeking advice on dosing and cycling Saw Palmetto.