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      community What's the deal with Zinc and DHT?

      in Chat  48 upvotes 2 years ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community Got my bloodwork results, need guidance!

      in Update  1 upvotes 1 year ago
      An 18-year-old male with hair loss is considering starting finasteride but is concerned about potential side effects like gynecomastia due to his prolactin levels. He seeks guidance on whether his bloodwork indicates it's safe to begin treatment.

      community L. reuteri (probiotic for Androgenic Alopecia)

      in Finasteride/Dutasteride  34 upvotes 2 months ago
      L. reuteri, a probiotic, is being explored for its potential benefits in treating androgenic alopecia, possibly enhancing finasteride's effects and reducing inflammation. The user combines this with finasteride, oral minoxidil, and other supplements, noting some improvement in hair loss.

      community Effect of finasteride if you already have low testosterone?

      in Treatment  1 upvotes 1 year ago
      A 24-year-old with a history of hair loss, low testosterone, and other health issues is seeking advice on treatments. They are considering options like topical and oral finasteride, oral minoxidil, PRP therapy, tretinoin, and microneedling.

      community Dht normal after taking fin and then dut

      in Treatment  2 upvotes 1 year ago
      The user has been taking dutasteride for 8 months and finasteride before that, with normal DHT levels but high estradiol and prolactin, leading to sexual side effects. The user is disappointed with these results.

      community Can aromatase inhibitors make dutasteride/finasteride useless?

      in Finasteride/Dutasteride  9 upvotes 2 years ago
      The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.

      community Dutasteride , bloodwork and dht.

      in Finasteride/Dutasteride  16 upvotes 2 years ago
      The user reported high testosterone and estradiol levels within range, but unexpectedly high DHT levels after using finasteride and dutasteride for hair loss. Another person suggested the dutasteride might be fake or a bad batch and recommended using the branded Avodart.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 3 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community New angles to attack beyond DHT

      in Research/Science  4 upvotes 1 year ago
      Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

      community Is this hierarchy of topical anti androgens accurate?

      in Ketoconazole  7 upvotes 4 years ago
      User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

      community (17M) Hair loss and Cystic Acnes / Dutasteride

      in Finasteride  109 upvotes 6 months ago
      A 17-year-old is using Finasteride and Minoxidil for hair loss, experiencing hair shedding and cystic acne. They are considering Dutasteride for acne but are concerned about potential side effects on genital development.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

      in Product  1 upvotes 8 months ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 3 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community Regrowth after 9 months of DHT blockers, and 6 months of HRT

      in Transgender  24 upvotes 7 months ago
      A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

      community Running Gear- Preemptive Treatment

      in Product 7 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community The lowest cyproterone dose to stop mpb

      in Treatment  4 upvotes 2 years ago
      The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

      community High testosterone and diffuse hairloss

      in Treatment  6 upvotes 5 years ago
      The user is experiencing diffuse hair loss due to high testosterone levels and has tried various treatments including finasteride, minoxidil, nanoxidil, keto/caffeine shampoo, dermarolling, and RU-58841 with limited success. They are seeking advice on safely lowering testosterone levels to manage hair loss.
      Eliminate/Confirm AGA based on blood report

      community Eliminate/Confirm AGA based on blood report

      in General  126 upvotes 11 months ago
      A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.