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      community common ideas amongst bald communities that doesnt help at all in my opinion

      in Chat  24 upvotes 1 week ago
      Balding is challenging, and relying on medications like finasteride is often seen as a better option than constantly shaving or trying to compensate in other areas. Many feel that societal expectations to "own it" or drastically change oneself to cope with baldness are unrealistic and burdensome.

      community Experience with Strut topicals?

      in Product  3 upvotes 1 year ago
      A user has been using a topical hair loss treatment with finasteride, minoxidil, and tretinoin for 4 years without satisfactory results and is considering switching to a different product due to concerns about effectiveness and company reliability. They are seeking others' experiences with Strut and alternative products before making a change.

      community (Europe) looking for advice on topical anti androgen use

      in Treatment  3 upvotes 8 months ago
      The user is using finasteride, minoxidil, and ciclopirox shampoo for hair loss and is considering adding a topical anti-androgen like RU58841, Clacosterone, or KX286. They have scheduled a hair transplant and are concerned about the cost and effectiveness of future treatments.

      community Topical bicalutamide vs ru58841

      in Female  1 upvotes 1 year ago
      A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.

      community Thinking about signing up for the setipiprant clinical trials

       4 upvotes 8 years ago
      The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.

      community any females on RU58841/minoxidil 2.5%?

      in Minoxidil  6 upvotes 4 years ago
      A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.

      community 21 months on topical minoxidil and full HRT

      in Transgender  214 upvotes 1 year ago
      The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.

      community Vicious male pattern baldness TINGLING ITCH!

      in Chat  7 upvotes 3 years ago
      A user struggles with male pattern baldness and a persistent tingling itch on their crown, trying various treatments like aloe vera, tea tree oil, and Nizoral without success. Another user suggests the itch might be psychosomatic, linked to worrying about hair loss.

      community Targeting multiple AGA mechanisms with commonly available substances

       4 upvotes 7 years ago
      The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

      community Spironolactone VS dutasteride for female pattern hair loss

      in Treatment  7 upvotes 1 year ago
      Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

      community How well can HRT reduce scalp tension?

      in Transgender  6 upvotes 3 years ago
      A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.

      community Fin, Testorone and Gyno Theory

      in Finasteride/Dutasteride  5 upvotes 4 years ago
      The conversation discusses managing gynecomastia symptoms potentially caused by finasteride use, with treatments including reducing finasteride dosage, using DIM, ashwagandha, tamoxifen, epistane, and arimistane. Users share experiences and advice on balancing testosterone and estrogen levels to address symptoms.

      community Balding really does affect you sometimes

      in Chat  228 upvotes 3 months ago
      A person is worried about balding affecting their relationship and is using minoxidil, finasteride, and dutasteride. They are advised to be honest with their partner and focus on self-acceptance, as many people don't care about hair loss.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Anyone else find themselves staring at other men with full heads of hair?

      in Chat  207 upvotes 4 months ago
      A 19-year-old discusses feelings of envy towards men with full heads of hair, sharing their experience with hair loss since age 16. They have been using oral minoxidil and topical finasteride for two years, with initial improvement but continued shedding, and are considering switching to dutasteride.

      community isoflavones to combat gyno?

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      Isoflavones from soybeans may help limit estrogen's effects on the body, potentially preventing gyno. However, surgery is the only way to remove gland enlargement.

      community My Theory Of Androgenic Alopecia

      in Research/Science  18 upvotes 4 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community What I hate about being told to shave my head

      in Chat  258 upvotes 8 months ago
      Hair loss challenges and identity issues, with opinions on using finasteride, minoxidil, and hair transplants versus accepting baldness. Some find shaving more work, while others stress personal choice and self-perception.

      community Why do people feel the need to comment on my hair when they know there's nothing I can do about it?

      in Chat  72 upvotes 2 years ago
      A 28-year-old started using finasteride and minoxidil for hair loss and is frustrated by insensitive comments from others about his balding, which is a sensitive topic for him. People, including a girl he's seeing, have made hurtful remarks, and the conversation includes discussions on societal double standards and advice to ignore such comments and focus on self-improvement.

      community Topical Dutasteride And Sperm Quality ?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      A user is concerned about the impact of topical dutasteride on sperm quality and potential long-term fertility issues. They are using microneedling with a 0.025% dutasteride solution and are seeking information on whether sperm parameters return to normal after stopping the drug.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Clavicular, The Daily, and what his rise means for hair

      in Chat 3 weeks ago
      The conversation critiques the influence of "Clavicular" on young men regarding hair loss treatments, highlighting the dangers of following unscientific advice and the rise of body dysmorphia. It emphasizes the importance of safe, medically advised treatments like minoxidil, finasteride, and dutasteride, while warning against reckless experimentation and early surgeries.

      community Is my friend lying about getting a transplant?

      in Transplants 3 months ago
      A person suspects their friend had a hair transplant instead of stem-cell injections due to a noticeably straight hairline. The discussion includes opinions on hair transplants, societal perceptions, and suggestions like using finasteride to maintain hair.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.