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      community PP405 mechanism question - looking for discussion

      in Treatment  7 upvotes 3 weeks ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community RU58841 2.5% in Minoxidil 5% 3ml twice a day - Less Hairfall "BUT"

      in Treatment  2 upvotes 2 years ago
      The user mixed RU58841 with Minoxidil for hair loss treatment and experienced reduced hair fall and thicker hair but stopped due to chest pain and muscle twitching. They plan to use a new routine without RU58841 or Finasteride due to side effects, including various topical treatments and peptides.

      community 19 | 4-5 months Fin & Min update

      in Progress Pictures 4 years ago
      A user who has been using finasteride and minoxidil for 4-5 months with 5000 IU of vitamin D daily to treat their hair loss, resulting in impressive progress. Other users have given advice about adding Vitamin K2 to the regimen.

      community Started seeing regrowth at month 5 of Fin

      in Is this regrowth?  12 upvotes 8 months ago
      A 24-year-old male experienced significant hair regrowth after 5 months of using Finasteride, with no other treatments like Minoxidil or microneedling. He also reported an increase in libido and no other side effects.

      community RU58841 has gotten rid of my acne

      in Product  1 upvotes 7 months ago
      RU58841, combined with 5% minoxidil, helped reduce acne and hair loss. Users discussed using RU58841 cream for acne and shared experiences with other treatments like finasteride and dutasteride.

      community Pp405 phase 2a clinical results

      in Research/Science  36 upvotes 9 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community Update: Chest discomfort from RU58841

      in Update  33 upvotes 2 years ago
      A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

      community Any one here on GHK-RU58841? Does it work?

      in Product 1 year ago
      GHK-RU58841 is used for hair loss, with positive results when combined with finasteride, stemoxydine, redensyl, and alfatradiol. Users report effectiveness after adding finasteride.

      community How much faith do you have in Kintor?

      in Research/Science  18 upvotes 4 years ago
      KX-826 is a potential hair loss treatment, with users discussing its effectiveness compared to finasteride and concerns about its trial results. Some users express skepticism about new treatments, while others discuss the potential of androgen receptor degraders and the need to manage drug resistance.

      community RU/Pyrilutamide access and purchase

      in Product  3 upvotes 3 months ago
      The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

      community Min / Fin - M21 - 1.5 Year Update - Multiple Sheds

      in Update  15 upvotes 10 months ago
      The user experienced significant hair regrowth using 5% topical minoxidil and 1mg finasteride daily, despite multiple shedding phases, and emphasizes the importance of starting treatment early and maintaining consistency. They advise against obsessing over online forums during shedding periods and recommend checking for scalp conditions like seborrheic dermatitis and ensuring proper nutrition.

      community Pyrilutamide vs Ru58841 thoughts

      in Research/Science  8 upvotes 3 years ago
      The user has been using Pyrilutamide (Pyril) for hair loss for a month alongside finasteride/dutasteride since 2021 but hasn't seen results. They are considering switching to RU58841 due to its many success stories, despite being skeptical about the legitimacy and testing of Pyrilutamide.

      community Finnasterid (1mg) 5 month results

      in Progress Pictures  429 upvotes 9 months ago
      The user shared positive results after 5 months of using oral finasteride, reporting no side effects and continued shedding but less than in the initial months. Other users discussed their experiences with finasteride and minoxidil, with some expressing concerns about side effects and others sharing their own progress and plans.

      community 21m, curious about what's going on with my hair

       6 upvotes 11 years ago
      A 21-year-old male with a thyroid condition noticed his hair thinning uniformly without a receding hairline. He is considering using a 5ARI to prevent further baldness if he starts TRT.

      community Five Months Progress - Min/Fin

      in Progress Pictures  15 upvotes 8 months ago
      The user shared five months of progress using oral finasteride, topical minoxidil, and supplements like biotin, zinc, omega-3, and collagen. They noted encouraging results, while others suggested trying oral minoxidil or microneedling for potentially better outcomes.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 10 months ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 7 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  98 upvotes 5 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.