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      community My personal thoughts on DHT. belive it or not

      in Research/Science 1 year ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 1 year ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Is this regrowth? 80 days in...

      in Is this regrowth?  56 upvotes 11 months ago
      The conversation is about hair regrowth using topical finasteride, minoxidil, and microneedling, with some users noticing new hair growth. The original poster also takes protein, biotin, and vitamin D supplements and prefers topical treatments due to concerns about side effects from oral finasteride.

      community My stack and 9 months progress (Nov, 2024 to July, 2025)

      in Is this regrowth?  33 upvotes 8 months ago
      The user shared their hair regrowth progress using a regimen including omega-3, flaxseed, EGCG, green tea, zinc, copper, probiotics, microneedling, topical finasteride, and minoxidil. Other users expressed skepticism about the effectiveness of the regimen, suggesting more proven treatments or considering a hair transplant.

      community Update On Massages and Nutrient Intake at N2 Stabilization

      in Update  1 upvotes 7 months ago
      The user shared their experience with hair regrowth using a natural approach, including a good diet, multivitamins, pumpkin seed oil, and scalp massages, without using minoxidil or finasteride. They emphasize this method for those with stabilized hair loss around Norwood 1.5 - 2, noting satisfactory progress over a year.

      community Rate my Hair loss prevention stack

      in Treatment  5 upvotes 4 months ago
      The user is using a comprehensive hair loss prevention regimen including Dutasteride, RU58841, topical treatments, red light therapy, microneedling, and supplements like Nutrafol, while avoiding Minoxidil. They also supplement with vitamin D and zinc and plan to start testosterone replacement therapy (TRT) in January.

      community Clascoterone ph3 results ready

      in Research/Science  8 upvotes 4 months ago
      Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.

      community He is claiming, he can treat alopecia

      in Chat  357 upvotes 3 months ago
      A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

      community 1 year Fin/Min + sporadic use of RU58841 (a few months here or there)

      in Progress Pictures  107 upvotes 4 years ago
      The conversation is about a person's one-year progress using finasteride and minoxidil for hair loss, with intermittent use of RU58841, showing improved hair quality, density, and thickness without side effects. Users complimented the improved appearance and suggested the longer hair also enhanced their look.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 2 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Half year update on crown balding reversal

      in Is this regrowth?  36 upvotes 4 months ago
      The conversation is about a user who started using finasteride to address crown balding, noticing reduced hair shedding and halted progression of male pattern baldness. The user also used a dermal stamp and expressed optimism about potential regrowth, despite a slight decrease in libido.

      community Small study on zinc and arginine

      in Research/Science  17 upvotes 5 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also touches on a study involving zinc and L-arginine.

      community NBA Guard Cole Anthony’s hairline revival

      in Chat  196 upvotes 2 years ago
      The conversation speculates on NBA player Cole Anthony's hairline improvement, suggesting possible treatments like hair transplant (HT) and medications such as finasteride and minoxidil. Some believe he may have had a hair transplant between August and November 2023, while others discuss the necessity of continuing medication post-transplant to maintain hair.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community Losing the genetic lottery - venting

      in Chat  64 upvotes 1 week ago
      The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

      community How effective is spironolactone?

      in Transgender  4 upvotes 3 years ago
      A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community Oral fin/min/biotin Stack 2 month progress pics

      in Progress Pictures  15 upvotes 2 months ago
      The conversation is about a user's progress with an oral treatment for hair loss using a stack of finasteride, minoxidil, and biotin over two months, noting stabilization after an initial shed. The user mentions using Hims Chews, which are effective but costly, and another user comments that biotin is ineffective.

      community Questions about alfatradiol logistics

      in Treatment  5 upvotes 2 years ago
      The user is seeking help with using Ell-Cranell for hair loss treatment. They are unsure about the correct application method and dosage. They also inquire about combining microneedling with topical alfatradiol and question a study that referred to alfatradiol as a hair growth inhibitor in male mice.

      community Minoxidil with Stemoxydine for hair growth?

      in Minoxidil  5 upvotes 4 years ago
      The conversation is about using stemoxydine in addition to minoxidil for hair growth. The original poster is considering adding stemoxydine to their hair loss treatment regimen.