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      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 1 year ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community Koshine has anyone ever tried this?

      in Treatment  1 upvotes 5 months ago
      Koshine is considered less effective than finasteride, dutasteride, and RU58841 for hair loss treatment. One user reported positive results with Koshine, but others found it ineffective.

      community RU58841 mixing with water solution

      in Research/Science  5 upvotes 4 years ago
      RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.

      community Is there any way to know for sure if hair thinning is just from fungal infection/ inflammation and would be reversed with just Ketoconazole 2%/ triamcinolone acetonide etc?

       2 upvotes 10 years ago
      The user is unsure if their hair thinning is due to fungal infection/inflammation or genetic factors and is hesitant to start Minoxidil, finasteride, and RU58841. They are currently using Ketoconazole 2% and triamcinolone acetonide and are concerned about potential side effects from other medications.

      community Hair and plants analogy and dht (serious)

      in Research/Science  2 upvotes 2 months ago
      Hair loss may be linked to DHT, which can both suppress and increase inflammation, potentially as a defense mechanism. Treatments like Minoxidil, Finasteride, and RU58841 are discussed, but the exact cause of hair loss remains unclear.

      community Head itch even though I use keto shampoo

      in Ketoconazole  3 upvotes 1 year ago
      The user experiences scalp itchiness despite using ketoconazole shampoo and is also taking oral finasteride and minoxidil. Suggestions include trying different shampoos like Head & Shoulders, using salicylic acid products, considering allergies, and consulting a dermatologist for alternatives like Ciclopirox.

      community Anyone tried Thicair? thoughts?

      in Product 11 months ago
      Thicair is a product combining microneedling and subdural vitamins for hair loss, containing ingredients like Panax Ginseng Root Extract and Copper Tripeptide-1. Users are skeptical, with one calling it "quackery."

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 2 years ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community RU58841 in germany eventually facing legal charges

      in Hair Systems  32 upvotes 1 year ago
      The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 7 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community RU58841 and some major questions?

      in Treatment  6 upvotes 2 years ago
      A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

      community Scarring Alopecia and NSAIDs?

      in Female  4 upvotes 5 years ago
      The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

      community Red and ichy pimples/rash from applying topical minoxidil

      in Chat  2 upvotes 5 months ago
      The user experienced red pimples and a rash from using topical minoxidil, possibly due to propylene glycol. Suggestions included seeing a dermatologist, switching to foam without propylene glycol, using Nizoral, and adjusting application timing.

      community GT20029: How It Works for Hair Loss - Hair Loss “Cure”

      in Research/Science  33 upvotes 4 months ago
      GT20029 is a potential treatment for androgenetic alopecia, addressing the root cause by targeting androgen receptors, unlike Minoxidil or Finasteride. It is seen as a preventative measure rather than a regrowth agent, with hopes for market release soon.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 2 years ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community A Short Recap on PP405 and AAD 2026

      in Update 3 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community New Approach to Ketoconazole or just waste of time?

      in Ketoconazole  21 upvotes 2 years ago
      The post discusses using 2% ketoconazole shampoo as a competitive androgen receptor antagonist for hair loss, applied for 1.5 hours daily. The user questions its effectiveness and potential benefits compared to finasteride and minoxidil.

      community My somewhat nuclear Hair loss prevention procotocol

      in Treatment  6 upvotes 2 years ago
      A 21-year-old male shared his extensive hair loss treatment protocol, which includes Dutasteride, RU58841, Ketoconazole shampoo, oral Minoxidil, pyrilutamide, MK677, dermastamping, and castor oil, and reported improved hair regrowth and overall well-being. He has experienced no side effects and has also improved his diet and lifestyle.

      community GHK Cu - is this the next best solution for hairloss?

      in Research/Science  22 upvotes 4 months ago
      GHK-Cu is discussed as a potential hair loss treatment, with claims of promoting hair growth and possibly reversing gray hair, though strong clinical evidence is limited. The user also mentions using Minoxidil, red light therapy, and microneedling.