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The conversation is about finding a source for RU58841 in Canada as an additional treatment for hair loss, alongside oral minoxidil and dutasteride. Alternatives like kx826 are suggested, with some users discussing prices and sources for these products.

The user shared progress on hair regrowth using 5% topical minoxidil, 2% keto shampoo, oral finasteride, and recently switched to daily dutasteride. They reported positive results without significant side effects and are hopeful for further improvement.

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

A user discussed using KeraXL serum for hair loss, which contains Biochanin-A from Red clover extract and Acetyl Tetrapeptide-3. They sought feedback on its safety and effectiveness.

The user has been using finasteride (1.25 mg oral) and minoxidil (5% topical) for 14 months, with recent addition of ketoconazole shampoo, and is experiencing ongoing hair shedding. Despite shedding, there is noticeable hair regrowth, though density remains a concern.

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Users are asked to share their experiences with Pyri/Koshine.

DutchFella1993 has been using a lotion with finasteride and minoxidil for hair regrowth with some success and is considering using ketoconazole shampoo daily to reduce scalp itchiness. There's concern about the harshness of daily shampooing and twice-daily lotion application, and one reply suggests that daily use of ketoconazole may damage hair and questions its effectiveness, while also noting that once-daily minoxidil application is sufficient.

The user underwent a DHI hair transplant with 3,066 grafts at Hairtec in the Netherlands and is using finasteride and minoxidil to restore hair, particularly at the crown. They plan to adjust minoxidil dosage and consult with a dermatologist in September.

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.

Kintor's Phase II U.S. trials for pyrilutamide and the process of pharmaceutical drugs coming to market, with a reply from someone who has just ordered 500mg of Pyrilutamide to start their own phase trials.

Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.

Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.

OP is experiencing dandruff and is considering switching from climbazole to ketoconazole, with suggestions to use Nizoral and a routine involving ketoconazole, coconut oil, and lemon. OP is also using minoxidil and finasteride for hair loss, and there are discussions about various shampoos and treatments for dandruff.

The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

The user is using oral dutasteride, topical minoxidil (Regaine foam 5%), and ketoconazole shampoo for hair loss, reporting good results with no significant side effects. The user is 26 years old and applies minoxidil once or twice daily.

The user shared progress pictures of their crown after using 5% minoxidil, finasteride, ketoconazole shampoo, microneedling, and PRP treatments. They have been using minoxidil, ketoconazole shampoo, and microneedling for 4.5 months, and finasteride for 2 months.

The user shared progress in hair regrowth using oral finasteride, topical minoxidil, and ketoconazole shampoo every other day, noting no side effects from finasteride. They expressed satisfaction with the results and optimism for further improvement.

People are discussing their experiences with kx-826 (pyrilutamide) for hair loss, using concentrations of 0.5% and 0.9%. They are sharing personal results and progress with this treatment.

PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

Kintor is testing Pyrilutamide with Minoxidil for hair loss. Users are skeptical about its effectiveness and concerned about limited treatment options if this fails.

People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

The conversation humorously discusses hair loss treatments, mentioning Minoxidil, finasteride, and RU58841. It suggests that affordable genetic therapy could be the ultimate solution.

This conversation is about a 21-year old male's success with using finasteride, minoxidil and ketoconazole shampoo to regrow his hair. He increased the finasteride dosage from 1mg 3x per week to 1 mg daily for maximum results. People in the thread commended him on his progress.

The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.

The user started oral finasteride on February 3, 2025, and uses topical minoxidil, Nizoral, derma stamping, Vitamin D3 + K2, and biotin/keratin for hair loss. They reported significant progress in 45 days.

A 32-year-old male shares his 5-year progress using finasteride, minoxidil, RU58841, and ketoconazole for hair loss. Despite consistent use, he feels his hair isn't as thick as before and is concerned about continued shedding and hairline miniaturization.