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      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Comeback is real from NW7?

      in Treatment  65 upvotes 6 years ago
      A 25-year-old who started losing hair at 16 and reached almost NW7 by 20 saw hair regrowth using a regimen including dutasteride, minoxidil, nizoral, and a dermaroller, along with supplements like biotin, zinc, and omega-3. After initial success, they experienced shedding, added more supplements and treatments, and sought advice on whether to continue; responses encouraged them to persist as shedding is often part of the hair regrowth cycle.

      community Somebody has gotta try this- HMI-115 reference anti-body

      in Treatment  13 upvotes 3 years ago
      The potential of using a specific antibody, HMI-115, as a treatment for hair loss alongside traditional treatments such as minoxidil and finasteride. The user suggests trying either a 240 mg or 30 mg dose to see if it works.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 3 years ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

      community Half year update on crown balding reversal

      in Is this regrowth?  36 upvotes 6 months ago
      The conversation is about a user who started using finasteride to address crown balding, noticing reduced hair shedding and halted progression of male pattern baldness. The user also used a dermal stamp and expressed optimism about potential regrowth, despite a slight decrease in libido.

      community Lost all my progress bc I went to jail :(

      in Update  67 upvotes 8 months ago
      The user lost hair progress while in jail due to stopping treatments like oral dutasteride, topical applications, and ketoconazole shampoo. They plan to restart their regimen and hope to recover in about 18 months.

      community 15 months of oral Finasteride + Minoxidil

      in Is this regrowth?  15 upvotes 6 months ago
      The user has been using 3mg oral Minoxidil and 1.1mg oral Finasteride for 15 months and plans to switch to 5mg oral Minoxidil, 1.1mg oral Finasteride, and 0.1mg oral Dutasteride. They have also used ketoconazole and salicylic acid shampoo for seborrheic dermatitis and hope to see more hair growth with the increased dosage.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Aged 51 testimony on hair recovery

      in Treatment  14 upvotes 3 months ago
      A 51-year-old shared their hair recovery journey using finasteride, minoxidil, and dermarolling, noting significant improvement in hairline and temple areas. They emphasize consistency and patience, while another user suggests adding topical kx-826 and melatonin for additional benefits.

      community Progress 6 months what do you say?

      in Progress Pictures  9 upvotes 5 years ago
      The user shared progress pictures after 6 months of using finasteride, minoxidil, dermarolling, vitamin D, and sulfate-free shampoo. They are concerned about ongoing hair loss and are considering adding dutasteride.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Anyone looking at peptides for hair?

      in Treatment  9 upvotes 4 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community Update: 14 months - NW Picard Progress

      in Progress Pictures  153 upvotes 5 months ago
      The user shared their hair regrowth progress using a combination of treatments including finasteride, dutasteride, minoxidil, tretinoin, Sulfogenz, KX-826, low-level laser therapy, and microneedling. They plan to continue medication for another year before considering a hair transplant, noting steady improvement but not major changes.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community ultimate nuclear stack? need more suggestions bruhh

      in Technology  2 upvotes 10 months ago
      The conversation discusses an extensive hair loss treatment regimen including dutasteride, GT20029, RU58841, pyrilutamide, minoxidil, microneedling, ketoconazole shampoo, and experimental compounds. The user humorously describes their approach as a comprehensive strategy to combat hair loss while maintaining hair growth.

      community 14 months on Fin, Total T 899, serum DHT 276 — high total T may still drive scalp DHT even when blood levels look controlled

      in Finasteride/Dutasteride  3 upvotes 1 month ago
      A 23-year-old male has been using finasteride and topical minoxidil for 14 months with slight improvement, but recent shedding led him to switch to a new minoxidil formulation without success. He is considering using topical RU58841 or dutasteride to better address scalp DHT, as his bloodwork shows high total testosterone and mid-range DHT levels.

      community 21 months microneedling plus 15 months Fin, Great Results!

      in Update  72 upvotes 6 years ago
      A user shared their successful hair loss treatment using 1.25mg finasteride daily, 2.5mm microneedling every 1-3 weeks, zinc pyrithione shampoo, occasional scalp massages, and 40% glycolic acid on temples. They reported significant progress over 21 months.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  12 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community Landon Donovan - celeb hair transplant

      in Transplants  265 upvotes 1 year ago
      Landon Donovan recently had a hair transplant, leading to noticeable changes in his appearance. The conversation revolves around his confidence and reactions to his new look.

      community 17 and Balding- Need treatment help and input

      in Chat  6 upvotes 6 years ago
      A 17-year-old in the UK seeks advice on mitigating hair loss until finasteride becomes an option at 19. Recommendations include using Minoxidil and considering other treatments like specific shampoos and dietary changes.

      community 6 MONTHS PROGRESS (HAIR TRANSPLANT)

      in Update  24 upvotes 1 month ago
      The user shared a 6-month update on their hair transplant progress, noting they still use oral minoxidil and dutasteride daily. They are pleased with the results but observe increased hair shedding during showers.

      community Age :-17 ,on topical fin and min

      in Is this regrowth?  194 upvotes 1 year ago
      A 17-year-old is using topical finasteride and minoxidil for hair regrowth. The effectiveness of these treatments is discussed, with some users noting progress and others suggesting more time is needed for significant results.

      community Kintor does not have abandoned KX-826 - ANNUAL RESULTS 2023

      in Product  8 upvotes 2 years ago
      The conversation discusses disappointment with the hair loss treatment KX-826 but notes that the company Kintor is still focused on developing and commercializing it, as stated in their 2023 annual report. The user questions the effectiveness of KX-826 in comparison to minoxidil's role in improving hair thickness and appearance.