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      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 6 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 9 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Today I start with this: RU58841

      in Progress Pictures  31 upvotes 3 years ago
      The conversation is about a person starting treatment with RU58841 for hair loss. They are asked to share progress pictures to show if the treatment is effective.

      community Kintor KX-826 Group Buy Feedback

      in Research/Science  29 upvotes 4 years ago
      The conversation is about a group of people trying KX-826 for hair loss, with no serious side effects reported after 25 days of use. Some participants are experiencing less scalp itch and shedding, but it's too early for definitive results.

      community 23 year old male 1mg fin everyday

      in Progress Pictures  41 upvotes 2 years ago
      A 23-year-old male shared his 4-month progress using 1mg finasteride daily, along with B-12 and D3+K2 supplements, to address hair loss. He sought feedback on using generic finasteride and shared his journey to regain confidence.

      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  12 upvotes 6 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community RU58841 and some major questions?

      in Treatment  5 upvotes 2 years ago
      A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

      community Has anyone tried CB-01-03 aka Clascoterone?

      in Research/Science  2 upvotes 1 month ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 2 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.
      21M, Thinning on Top with Family History, Seeking Treatment Options

      community 21M, Thinning on Top with Family History, Seeking Treatment Options

      in General  59 upvotes 3 months ago
      A 21-year-old with a family history of early balding is advised to see a dermatologist to confirm androgenetic alopecia (AGA) and consider treatments like finasteride or dutasteride to prevent further hair loss, and minoxidil, possibly with tretinoin, to regrow hair. Caution is advised with oral minoxidil, and a cardiologist should be consulted before use.

      community Just started Dut+Mim, should I add RU58841?

      in Treatment  1 upvotes 3 months ago
      A 23-year-old started using 0.5mg Dutasteride and 2.5mg Minoxidil daily for hair loss and is considering adding RU58841 or GHK-cu. Users suggest waiting a few months before adding anything and mention Koshine's kx-826 as a potentially better alternative to RU58841.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  20 upvotes 2 months ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

      community 3 hair transplants | 11,102 grafts | 28 yrs old | NW 6/7

      in Transplants  149 upvotes 1 year ago
      A 28-year-old underwent three hair transplants totaling 11,102 grafts at Eugenix, using finasteride and minoxidil to manage advanced hair loss. Despite limited density, the results are satisfactory, allowing the individual to feel presentable without a hat.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 3 weeks ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community RU/Pyrilutamide access and purchase

      in Product  3 upvotes 3 months ago
      The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 2 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community How long still for CB-03-01? (breezula)

      in Question  7 upvotes 6 years ago
      The conversation is about the release timeline for clinical trial results and the availability of Breezula, a hair loss treatment. The user is not comfortable buying it as a research drug from China.

      community Gonna start on Finasteride Tomorrow! 🤞

      in Chat  13 upvotes 2 years ago
      A 19-year-old male plans to start finasteride due to hair thinning after using creatine. He seeks advice on finasteride's effectiveness, especially for Asians.