A user shared their 7-month progress using only topical finasteride for hair loss. They recently started a new, non-FDA treatment and will evaluate its effectiveness in 6 months.
RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.
Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.
The user is happy with their hair regrowth after using 2.5mg Minoxidil and 1mg Finasteride daily for six months. They are considering adding microneedling to their treatment.
The user has been using finasteride, minoxidil, a dermastamp, and red light therapy for six months with no visible improvement since the three-month mark. Other users noted improvement, particularly in the left temple area, and encouraged the user to continue.
Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.
A user shared their 6-month progress on finasteride but stopped due to financial issues, seeking advice on whether to continue. Replies strongly advised resuming finasteride to maintain progress, with suggestions for affordable options.
PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.
A user shared their 5-month hair loss treatment progress using 1mg finasteride, topical minoxidil, biotin, Nizoral shampoo, and weekly dermarolling. Replies noted the user's hair was already thick, and there was interest in trying topical minoxidil.
A 26-year-old male experienced hair regrowth and increased density after 6 months using oral finasteride and minoxidil tablets, along with a derma pen, multivitamins, omega-3, creatine, and L-citrulline. He plans to add RU58841 soon and is hopeful for further improvement.
A user tried the Rapid Minoxidil Response Test (TrichoGene) and found they don't respond to topical Minoxidil, so they added tretinoin. The test is available internationally, and another user is considering ordering it.
SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.
High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.
Breezula (clascoterone) is expected to be available by late 2026, showing good long-term results with minimal side effects. KX-826 (pyrilutamide) acts faster but is still in earlier development stages.
The user is using Minoxidil, RU58841, CB-03-01, WAY-316606, Ketoconazole, MK-677, and derma stamping to treat hair loss and has noticed new hair growth, especially around the temples and hairline. They apply different treatments at various times of the day and have seen improvements in skin condition and body hair texture.
A user is seeking advice on increasing graft survivability after a hair transplant, mentioning PRP, Mesotherapy, Stem Cell injections, and considering L-Arginine before starting Minoxidil. They are looking for ways to support blood flow before applying Minoxidil.
A user shared their 5-month hair regrowth progress using 5% topical minoxidil daily, microneedling weekly, and ketoconazole shampoo twice a week. Some suggest adding finasteride to maintain results, while others commend the current regimen's effectiveness.
The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.
A 26-year-old man shared his 6-month hair regrowth progress using 0.25% topical finasteride, 5% topical minoxidil, Trichosol, and weekly derma stamping. He plans to start using a lotion with dutasteride and azelaic acid.
A 49-year-old is updating on hair regrowth progress using finasteride, minoxidil foam, tretinoin cream, and ketoconazole shampoo. They report thicker, darker hair and reduced scalp itch after switching to minoxidil foam.
The conversation is about hair regrowth progress using topical finasteride 0.1%, minoxidil 10%, ketoconazole shampoo, and weekly microneedling. The user plans to continue the treatment for another year to assess its effectiveness.
The user shared progress pictures showing significant hair regrowth after 6 months of using 1mg finasteride and 2.5mg minoxidil, with no side effects reported. They added Nizoral to their routine to address an itchy scalp.
The conversation discusses the sale of a premixed KY19382 solution for research purposes, highlighting previous unsuccessful group buys and the formulation process. Prices and purchasing options for KY19382 solutions and powder are provided.
After 7 months of using topical finasteride/minoxidil, microneedling, and Nizoral shampoo, the user believes they are seeing hair regrowth. They are seeking further advice to improve their results, excluding hair transplant options.
Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.
The user experienced significant hair regrowth using a regimen of minoxidil 5% twice daily, finasteride 1 mg daily, microneedling, ketoconazole 2% twice a week, and occasional castor and coconut oil, along with daily scalp massages. They are optimistic about reversing their Norwood 5/6 hair loss.
A user shared their positive experience with hair regrowth after six months of using minoxidil and finasteride, reporting no side effects. They showed progress photos and expressed hope for full restoration of their hair.
A 27-year-old male with androgenetic alopecia has been using finasteride, topical minoxidil, and microneedling for over six months to stabilize hair loss and prepare for a potential hair transplant. While some users suggest switching to dutasteride and increasing minoxidil usage, others note minimal progress, with some hair stabilization but concerns about thinning at the crown.