Maneup GHK-Cu peptide was used for hair loss, resulting in some hair growth in the receded hairline, but the new hairs were dry and split easily. Users discussed their experiences with this treatment.
TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.
The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.
Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hair follicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.
Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.
RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.
Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.
A user suggests using a poop-based solution for hair growth, comparing it to fertilizing nails. Others humorously respond, with one mentioning microneedling as a similar concept.
A 28-year-old male shares his hair regrowth progress using finasteride, topical and oral minoxidil, hair peptide serum, ketoconazole shampoo, dermastamping, multivitamins, and a high-protein diet. He reports noticeable hair growth and minor side effects, emphasizing patience as key to success.
The conversation discusses various supplements and vitamins like Vitamin D3, K2, Biotin, Iron, Zinc, and B Vitamins for improving hair health. It also mentions a combination of Tocotrienols, Pycnogenol, Saw Palmetto, Pumpkin Seed Oil, Stinging Nettle, and Myricetin for stabilizing hair, with Saw Palmetto, Pygeum, and Stinging Nettle noted for thickening hair despite side effects.
A woman using minoxidil for hair loss is trying hair fibers but finds they look like dandruff. Suggestions include using pomade, Derm Match, matte eye shadow, mascara, and spray applicators for a more natural look.
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
The shampoo discussed is mainly for volumizing and not effective for hair loss. Users suggest using regular shampoo and relying on medications like Minoxidil, finasteride, or RU58841 for hair loss treatment.
The user treated seborrheic dermatitis and hair loss with a routine including sulfate-free tea tree oil shampoo, ketoconazole shampoo, minoxidil foam, microneedling, and supplements like Omega-3 and Vitamin-D. They experienced significant hair shedding initially but saw improvement over a year.
The user experienced continued hair loss and scalp itch despite using finasteride and switching to dutasteride. They sought advice on managing these issues, with suggestions including adjusting medication frequency and trying different shampoos.
To increase hair density appearance, options include using hair fibers, volume powders, scalp micropigmentation, and a combination of sea salt and holding sprays. Tape-in extensions and clip-in fringes are also considered, but cost and maintenance are concerns.
A 20-year-old shared their experience of reversing hair loss without using minoxidil or finasteride, instead relying on supplements like biotin, collagen, fish oil, saw palmetto, and various vitamins. They emphasized the importance of a balanced supplement schedule and noted improvements in hair health without experiencing additional shedding.
The product being promoted is likely ineffective for hair regrowth, as it lacks key ingredients like minoxidil and finasteride, and may rely on deceptive marketing tactics such as lighting tricks. Users suggest that proven treatments like minoxidil and finasteride are more reliable for hair loss.
The user has been experiencing aggressive hair loss despite using finasteride, minoxidil, dutasteride, ketoconazole, and derma rolling. Suggestions include continuing current treatments, considering RU58841, checking for deficiencies, and possibly trying collagen supplements or oral minoxidil.
A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.
The conversation suggests that a 22-year-old male may regrow his hair using dutasteride and minoxidil without needing a hair transplant, advising to continue treatment and assess progress after 1-2 years.
The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.
A user is experiencing renewed hair loss despite using minoxidil and finasteride for two years and is considering options like dutasteride, increasing finasteride dosage, or starting microneedling. Respondents suggest waiting another month before making changes, consulting a dermatologist, and potentially adjusting the treatment regimen.
User reported hair regrowth and thicker hair after using rosemary oil, zinc, biotin, vitamin D, and a better diet. They believe rosemary oil contributed the most to the improvement.
Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. A secret to applying Toppik Hair Building Fibers is shared, and a possible reason is to help people apply Toppik.
Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.
Shampoos are unlikely to cause permanent hair loss; hair loss is more likely due to male pattern baldness (MPB). The user is advised that losing hair in the shower is normal, and to avoid shampoos with sodium sulfate.
A user reports positive results with finasteride, noticing thicker hair and regrowth at the temples and hairline. Another user shares their experience with minoxidil, noting small hairs that haven't grown, and plans to add finasteride to their regimen.
PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.
PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.