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      community Pyrilutamide isn’t failed at all.

      in Technology  11 upvotes 2 years ago
      Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

      community SETIPIPRANT PGE2 GROUP BUY AND PIONEERING HAIR GROWTH

       6 upvotes 10 years ago
      The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.

      community Sharing what worked for me (PCOS related hair loss)

      in Female  35 upvotes 2 years ago
      A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.

      community Help labing up hair preservations

      in Research/Science 2 years ago
      The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.

      community Mineral deficiencies vs MPB vs Thyroid

      in Chat  9 upvotes 1 year ago
      The user experienced hair improvement using a topical finasteride, minoxidil, and tretinoin combo, along with supplements like zinc, copper, magnesium, vitamin D3, K2, iodine, and boron. They believe these changes are due to addressing mineral deficiencies and possibly thyroid issues, despite skepticism from others.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 5 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

      in Product  1 upvotes 3 months ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  48 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community will pp405 be able to bring my lost temple area back to the game?

      in Research/Science  10 upvotes 3 months ago
      A user is concerned about hair loss in the temple area despite using Minoxidil and finasteride for 10 months and is curious if PP405 can help. Responses indicate uncertainty about PP405's effectiveness, with some optimism about future treatments and AI speeding up drug discovery, but emphasize waiting for clinical trial results.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 4 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 3 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Micronutrient testing, deficiencies, etc.

      in Treatment  4 upvotes 4 years ago
      Micronutrient testing and deficiencies related to hair loss, particularly androgenetic alopecia (AGA). Discussion includes the impact of iron, selenium, zinc, copper, folate, B12, vitamin E, vitamin D, amino acids, and fatty acids, alongside treatments like dutasteride or finasteride.

      community Bimatoprost (Lumigan) for MPB?

      in Treatment  4 upvotes 3 years ago
      The conversation discusses using Bimatoprost for eyebrow regrowth and its potential use on the hairline, with concerns about cost and side effects. Alternatives like topical Minoxidil are mentioned, but the user is worried about aging and acne.

      community Topical VPA - Anyone experiences here?

      in Question  2 upvotes 8 years ago
      The conversation is about using topical valproic acid (VPA) for hair loss, focusing on its application method, usage frequency, and combination with other treatments like micro-needling. No specific experiences with VPA were shared.

      community Procapil - Has anyone heard of it?!

      in Research/Science  1 upvotes 3 years ago
      The conversation discusses Procapil, a treatment for hair loss containing Apigenin and Oleanolic acid. Users are sharing their experiences and asking if anyone has tried it.

      community Finasteride gives me seb derm. Thoughts on zinc or other options?

      in Chat  16 upvotes 4 years ago
      A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  73 upvotes 1 year ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.