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      community Horrible news, Stemson Therapeutics has shut down

      in Technology  195 upvotes 1 year ago
      Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

      community PP405 Phase 2a press release with early results

      in Research/Science  697 upvotes 10 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Getting PP405. Now…. or as soon as possible

      in Research/Science  146 upvotes 10 months ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  12 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Pyrilutamide from Hairlisciously? Other suppliers?

      in Treatment  8 upvotes 3 years ago
      The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

      community Figuring out my own experimental protocol

      in Treatment  10 upvotes 2 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community Creatine and increased MPB Hair Loss

      in Chat  10 upvotes 4 years ago
      Creatine may increase hair loss in those with male pattern baldness (MPB) due to increased DHT, but whey protein generally does not affect hair loss. Finasteride and minoxidil are used to manage hair loss, and some users report increased shedding with creatine but not with whey protein.

      community Pyrilutamide isn’t failed at all.

      in Technology  11 upvotes 1 year ago
      Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

      community Verteporfin trials in hair transplant patients begin

      in Transplants  43 upvotes 3 years ago
      A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.

      community Saw an opinion on PP405 and sharing

      in Technology 1 month ago
      PP405 is discussed as a potential adjunct therapy for hair loss, with skepticism about its effectiveness and trial results. Users mention combining it with finasteride and minoxidil for better results, while others debate the root causes of hair loss and the limitations of current treatments.

      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community Any Indians using Minichek F 5% ???

      in Minoxidil  2 upvotes 1 year ago
      A user asks about experiences with Minichek F 5% with Procapil, specifically its drying time. Responses discuss the effectiveness and drying time of the treatment.

      community Has anyone tried KeraXL before?

      in Treatment  1 upvotes 2 years ago
      A user discussed using KeraXL serum for hair loss, which contains Biochanin-A from Red clover extract and Acetyl Tetrapeptide-3. They sought feedback on its safety and effectiveness.

      community Pyrilutamide - Worth it if can’t use Fin?

      in Research/Science  4 upvotes 11 months ago
      Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

      community Thinking about adding PRP - any real downsides?

      in Treatment  7 upvotes 6 months ago
      The user has been using minoxidil, finasteride, dermastamping, and Nizoral for hair loss with initial success but is considering adding PRP due to slowed progress. Concerns about PRP include potential ineffectiveness and whether it could harm existing hair growth or interfere with current treatments.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  173 upvotes 5 months ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community Shiseido (RepliCel) likely to cost around $1000

       5 upvotes 10 years ago
      RepliCel's potential hair loss treatment may cost around $1000 and aims to protect hair follicles from DHT, possibly reversing some miniaturization. It is not considered a cure and may be most effective in early hair loss stages, with its main advantage over finasteride being the lack of sexual side effects.

      community Losing the gains and frontline of battle

      in Progress Pictures  59 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the use of dutasteride, finasteride, and other methods like PRP, laser, and mesotherapy. Despite these treatments, the user is experiencing hair loss, and others suggest consulting a dermatologist, considering alternative treatments, and addressing potential scalp inflammation.

      community European release of clascoterone

      in Research/Science  12 upvotes 1 week ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.