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      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community how to compound topical cyclosporine

      in Treatment  8 upvotes 3 years ago
      The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.

      community Actifolic RU58841 and others Scam?

      in Treatment  6 upvotes 3 years ago
      Actifolic's RU58841 and Pyri products are perceived as ineffective, with users reporting no side effects or improvements, suggesting possible quality issues. Users recommend alternative sources and emphasize the importance of timing when using RU58841 with Minoxidil.

      community Topical Min 5% - Keto 2% shampoo 2x week - Tretnoin 0.025% - 6 Months update

      in Is this regrowth?  13 upvotes 9 months ago
      The user is experiencing hair loss and has been using topical Minoxidil 5%, Keto 2% shampoo, and Tretinoin 0.025% for six months, with plans to start topical Finasteride 0.1% soon. They are advised to focus on DHT blockers like Finasteride and consider additional tests and supplements to address potential deficiencies and scalp health.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 8 months ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Interested about what other adjunct therapies people are trying & whats working?

      in Treatment  7 upvotes 2 years ago
      The conversation discusses alternative hair loss treatments beyond the commonly used Minoxidil and Finasteride. One user is trying diclofenac gel, caffeine + antioxidant serum, finasteride, ketoconazole shampoo, and has stopped using Minoxidil due to ineffectiveness, while another user has adopted lifestyle changes like exercise, diet, stress reduction, and topical caffeine, along with scalp massages and microneedling.

      community What ketoconazole shampoo do you use?

      in Ketoconazole  6 upvotes 11 months ago
      Users discuss ketoconazole shampoos for hair loss, mentioning Nizoral, selsun blue, and alternatives like prescription strength options and compounded lotions to reduce dryness. Some users suggest using finasteride and minoxidil instead, questioning the cost-benefit of ketoconazole.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  36 upvotes 8 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 6 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Information regarding Kintor’s GT20029

      in Product  40 upvotes 3 years ago
      The conversation discusses skepticism about the effectiveness of new hair loss treatments, mentioning that despite 40 years of research, only accidental discoveries like Minoxidil and Finasteride have been made. It also notes that drug development is a slow process, often taking a decade or more to bring a new drug to market.

      community Should i try 0.25/0.5mg or topical after sides on 1mg

      in Finasteride  96 upvotes 4 months ago
      The user experienced chest soreness and mild gynecomastia after taking 1mg finasteride three times a week, which resolved after stopping the medication. They are considering trying a lower dose or topical finasteride to avoid side effects.

      community Topical - Dosage help (0.3% FIN per mL?)

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user is considering starting a topical treatment for hair loss, using a spray containing 0.3% finasteride, 5% minoxidil, and 0.01% tretinoin. They are questioning the dosage and considering reducing the application to achieve 0.15% finasteride and 5% minoxidil.

      community Verteporfin to deminiaturize follicles

      in Research/Science  7 upvotes 3 years ago
      User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

      community Combining Ru58841 with my Topical Formula

      in Research/Science  3 upvotes 9 months ago
      A user is combining RU58841 with a topical formula containing finasteride, dutasteride, minoxidil, triamcinolone, caffeine, and other ingredients. They have just started using it and report no side effects so far.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community 2 months on topical fin/min ...

      in Update  153 upvotes 1 year ago
      The user has been using a combination of 0.3% topical finasteride, minoxidil, ketoconazole, and microneedling once a week for two months with positive results and no side effects. They apply the treatment daily using a spray and have short hair, which makes application easier.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  82 upvotes 9 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community Ru58841 stops seb derm ( the itching)?

      in Treatment  8 upvotes 2 years ago
      RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.