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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 9 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 9 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community who in here has used ru58841 , and how did it go

      in Treatment  8 upvotes 5 months ago
      RU58841 had mixed results for hair regrowth, with some users experiencing no change and others noting regrowth but also side effects like libido issues and chest pain. Some users combined it with other treatments like finasteride and dutasteride, with varying effectiveness.

      community Self-Experiment - Topical Rapamycin or a-KB

      in Treatment  4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community Pre-mixed RU58841 in the KB solution vs PG solution?

      in Treatment  4 upvotes 4 years ago
      Choosing between KB and PG solutions for applying RU58841, considering factors like scalp oiliness and absorption. Some users prefer KB for being gentler, while others use PG and recommend washing hair before application for better results.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 11 months ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.

      community What’s needed to mix ru and k&b solution?

      in Research/Science  2 upvotes 1 year ago
      Mixing RU58841 with a solution for hair loss treatment, with suggestions to use propylene glycol and ethanol instead of k&b solution due to scalp irritation. Recommendations include using ketoconazole shampoo for itchiness and considering oral minoxidil if topical causes irritation.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

      in Product  1 upvotes 2 months ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community Legit or Snake-oil Alike Service

      in Technology  3 upvotes 1 year ago
      Hair therapy advertisements claim to use a mix of fallopia multiflora, ginseng, angelica sinensis, and vitex rotundifolia for hair growth. A user dismisses it as fake.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community How to mix ru and where to buy?

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses how to mix RU58841 for hair loss treatment, including the need for powder form to adjust doses and different mixing methods for absorption. It also inquires about reputable sources for purchasing RU58841 with fast shipping.

      community Why I still have faith in KX-826

      in Research/Science  54 upvotes 1 year ago
      KX-826 shows promise for hair maintenance at higher doses with minimal side effects, despite failing Phase III trials. The user believes it is more effective than Minoxidil, Finasteride, and RU58841.

      community Microneedling alone and rosemary/peppermint oil

      in Microneedling  7 upvotes 1 year ago
      A user is using microneedling and rosemary/peppermint oil to treat hair loss, avoiding chemicals due to potential side effects. They have seen baby hairs growing after five weeks and plan to continue for a year.

      community Best, possible, or experimental growth agonists that AREN'T MINOXIDIL.

      in Research/Science  4 upvotes 5 years ago
      Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.

      community Is 8% ru58841 significantly stronger than 5%

      in Chat  20 upvotes 2 years ago
      A user increased their RU58841 treatment from 5% to 8% to combat hair loss and is questioning the effectiveness of the higher dosage. Another user shared their extensive hair loss treatment regimen, suggesting that while 8% RU58841 might not significantly change results, it's worth trying as individual responses vary.

      community The following ingredients dramatically reduced hairfall for me after 3 months

      in Chat  35 upvotes 4 years ago
      The original poster found that using rosemary oil, peppermint oil, jojoba oil, oral castor oil, head massages, ketoconazole shampoo, omega-3 fatty acids, and a multivitamin reduced their hair loss from 150 to 50 hairs a day. Another person reported a significant drop in hair loss using a similar oil blend with additional ingredients.

      community Are Ru58841/Kx826 effective as fin?

      in Treatment  1 upvotes 1 year ago
      The user is considering switching from topical finasteride to RU58841 or KX826 due to side effects like low libido and ED. They are also using oral minoxidil and considering low-dose saw palmetto to maintain their hairline.