Search

everythingexperts & clinicslearnresearchcommunity

for

Search:↓

A new hair loss treatment shows promise in mice but is unproven in humans. Effective treatments include finasteride and minoxidil.

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

A 22-year-old experiencing hair loss and persistent scalp itchiness since age 16 has tried various treatments, including finasteride, ketoconazole shampoo, and dietary changes, with no success. Suggestions include consulting a knowledgeable dermatologist, considering seborrheic dermatitis, and trying different shampoos like Selsun Blue or those with selenium sulfide.

The user is concerned about having a straight, low hairline after a hair transplant and is unable to take finasteride due to high estrogen and prolactin levels. They have used minoxidil with limited success and are considering further transplants to lower the hairline, while others suggest the risks of using up donor hair too quickly.

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

The conversation discusses the impact of vitamins, stress reduction, and appropriate shampoo on hair health, with the original poster noting slight improvements after two months of using vitamins B5, B6, zinc, and a suitable shampoo. Many users express skepticism about the effectiveness of vitamins for hair loss unless there is a deficiency, emphasizing the importance of addressing DHT and considering 5AR inhibitors.

The user replaced finasteride with saw palmetto due to availability issues and experienced side effects, leading to adjustments in their regimen. They use saw palmetto, minoxidil, Nizoral, and a dermaroller, reporting reduced side effects and some benefits, with hair fall ranging from 5 to 20 hairs daily.

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

The user reported noticeable hair improvement after nearly two months using topical minoxidil twice daily, finasteride 1mg daily, and weekly microneedling, along with lifestyle changes like reducing alcohol consumption. They experienced minimal shedding and no significant side effects from finasteride.

Creatine may worsen hair loss in some, especially with androgenic alopecia, but evidence is mixed. Some users experience no hair loss when using creatine with minoxidil and finasteride, while others notice increased shedding.

People are discussing JXL-069 (PP405) for hair loss, with some experimenting with a 0.05% topical gel. Concerns about safety and efficacy persist due to limited testing and lack of official approval.

A 31-year-old male is using a hair loss treatment routine that includes daily 0.5mg dutasteride, 5% minoxidil, microneedling, biotin, vitamin D, omega-3 supplements, and alternating shampoos to restore hair density. He reports no side effects or noticeable regrowth yet but feels optimistic about the process.

Finasteride users discussing creatine's impact on hair loss. Most believe creatine doesn't significantly affect hair, with some reporting no issues and others experiencing thinning.

A 36-year-old experienced significant hair regrowth using minoxidil, finasteride, and tretinoin with minimal side effects. He plans to continue the treatment, hoping for more targeted solutions in the future.

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

A user falsely claimed to use 2.5mg of dutasteride by using someone else's photo, which actually showed results from finasteride. The conversation discusses the challenges and skepticism around hair loss treatments like dutasteride and finasteride.

A user shared progress pictures after 2 years on 0.5mg finasteride daily, also using minoxidil, showing significant hair improvement. The user noted their hairline is almost fully recovered.

People are discussing why barbers often don't mention their clients' hair loss, with some sharing personal experiences where barbers did suggest treatments like finasteride (Fin) or mentioned the possibility of hair transplants. Some barbers avoid the topic to not offend clients, while others openly discuss it and recommend treatments or acknowledge the issue when asked.

The user shared a 15-month hair loss treatment update using Dutasteride (0.5mg/day), Minoxidil (5% foam twice daily), Nizoral (1% every 3 days), and a 1.5mm derma roller (twice a month), along with a multivitamin, exercise, low sugar diet, hydration, and consistent sleep. They started seeing results after 6-9 months, with significant improvement at the 1-year mark, and apply Minoxidil the day after derma rolling.

The conversation is about Jordan Peterson allegedly getting a hair transplant, with various users mocking his way of speaking and debating the ethics of him potentially hiding the procedure. Some users discuss the natural look of the transplant and the implications of getting one at an older age.

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

A 23-year-old male shared his 4-month progress using 1mg finasteride daily, along with B-12 and D3+K2 supplements, to address hair loss. He sought feedback on using generic finasteride and shared his journey to regain confidence.

Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

The conclusion of the conversation is that experiencing shedding while using finasteride and minoxidil is a common occurrence, and it is likely a part of the hair growth cycle. Many users have reported regrowth and improvement in their hair density after the shedding phase.

The conversation suggests that changing diet and lifestyle has little to no effect on male pattern baldness (MPB), which is largely determined by genetics. Some individuals noted personal improvements in hair condition with healthier diets, but the consensus is that diet alone cannot prevent or reverse MPB.

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

Donald Glover's (aka Childish Gambino) hair transplant results, which appear to be moderate with around 1000 grafts. Various users discuss the previous and current appearance of his hairline and speculate that he may have used medications like Minoxidil or finasteride to stabilize before getting a transplant.