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      community How long for RU58841 to absorb?

      in Treatment  4 upvotes 1 year ago
      The user is concerned about safely using RU58841 around cats and wonders if applying it 2 hours before a shower is as effective as leaving it overnight. The discussion focuses on the absorption time and effectiveness of RU58841.

      community GT20029 Phase 2 results are out

      in Treatment  60 upvotes 6 months ago
      GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.

      community Ru 58841 and essential oils question

      in Treatment  3 upvotes 4 years ago
      The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.

      community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

      in Transgender  611 upvotes 1 year ago
      The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

      community Running Gear- Preemptive Treatment

      in Product 8 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Pyrilutamide solution question

      in Research/Science  8 upvotes 3 years ago
      The conversation is about the stability of pyrilutamide in different solutions. The user is asking if a 70/30 ethanol/pg solution with 4% water will degrade pyrilutamide.

      community Please! Need help for ru58841…

      in General  95 upvotes 1 year ago
      The user experienced significant hair loss after using RU58841 for a week and is seeking advice on recovery. They previously had side effects from finasteride and dutasteride.

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  20 upvotes 2 years ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.

      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  11 upvotes 8 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Dutasteride/RU/MIN will NOT work for everyone.

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      Hair loss treatments like Dutasteride, RU58841, and Minoxidil may not work for everyone, as some individuals experience no improvement despite extensive use and research. Genetic factors can play a significant role, and standard treatments may not be effective for all.

      community DUPA hair loss - What's the real deal ?

      in Research/Science  10 upvotes 3 years ago
      A 25-year-old male with DUPA (diffuse thinning including the donor area) has not seen improvement after 14 months on finasteride. He's considering switching to dutasteride (DUT) after advice from a hair loss YouTuber and is also contemplating trying RU58841.

      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 4 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community Scams by hair transplant, prp, GFC clinics i faced 24/m. Is there a dna test that shows which meds are more suitable to individual saw a post link below

      in Is this regrowth? 8 months ago
      The user shares their experience with hair loss treatments, including oral finasteride, oral minoxidil, and a topical lotion for dandruff, expressing dissatisfaction with past treatments like PRP and hair transplants. They seek advice on a DNA test to determine suitable medications and express frustration with dermatologists' advice.

      community 18M progression pt.3 (6 months)

      in Progress Pictures  744 upvotes 3 years ago
      User started balding at 16 and began treatment at 18, using RU58841, minoxidil, derma rolling, and peptides. After 6 months, they experienced significant hair regrowth and are happy with the results.

      community What are we thinking about this SCUBE3 boys

      in Product  7 upvotes 8 months ago
      SCUBE3 is a promising new molecule that can restart hair growth by reawakening dormant hair follicles. Users express skepticism about its availability timeline, with some hoping for release by 2026.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  102 upvotes 7 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.