PP405 shows promising results for hair density improvement, potentially outperforming Minoxidil in a shorter time. However, its public release is expected around 2029/2030, and its cost and availability remain uncertain.
The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.
A 24-year-old male has been using finasteride for 7 months and noticed thinning hair, especially when wet, and is concerned about the effectiveness of the treatment. Suggestions include continuing finasteride, considering minoxidil, and possibly trying micro-needling.
The conversation is about how to effectively apply 1mL of a topical hair loss treatment, Pyrilutamide, to cover the entire scalp. One user suggests making a 2.5 mg/mL solution and using 2mL for better coverage.
The user shared progress pictures over four months using topical finasteride, topical and oral minoxidil, topical RU58841 daily, and oral dutasteride once a week. The pictures are spaced about a month apart.
Clascoterone 5% shows promising hair growth results but is criticized for high cost and unclear effectiveness compared to other treatments like finasteride. Glenmark is testing a combination of Clascoterone 7.5% and Minoxidil 5% in India.
The user's progress with treating their hair loss with finasteride and minoxidil, as well as using a derma-roller infrequently and Nizoral shampoo twice a week. They discussed how helpful it was for the user to post comparison pictures with the same angle and lighting in each.
A 21-year-old male is using a Minoxidil (10%) and Finasteride (0.1%) topical solution with a Keraglo Men tablet for hair loss, experiencing positive results without side effects. He advises another user to prepare questions for a dermatologist visit and discusses potential treatment adjustments.
Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.
The conversation is about a person's 3.5-month hair regrowth progress using a combination of 8% topical minoxidil with 0.1% finasteride and 0.01% tretinoin, 5 mg oral minoxidil, and weekly use of a 1.5mm dermapen.
This user experienced improvements in their hair density and texture through the use of finasteride (1.25mg) and minoxidil (5%) applied topically once a day over 8 months, with no reported side effects other than slightly lowered libido.
The user experienced significant hair regrowth using 7% minoxidil, 0.3% finasteride, and derma stamping over nine months. They reported no side effects and noticed results around 3-4 months, with faster progress when using derma stamping 2-3 times a week.
The conversation discusses hair regrowth progress after 2.5 months using pyrilutamide and minoxidil. Participants note visible improvement in a short time.
A 30-year-old with diffuse thinning and a balding crown is using a treatment regimen of a 2-in-1 pill containing finasteride, minoxidil, and biotin, along with various supplements. After two weeks, no side effects have been experienced, and updates with pictures will be posted monthly.
The user shared a 10-month hairline update using 5% topical Minoxidil and 2.5% oral Finasteride, noting some improvement despite a second shedding phase. They switched to oral Minoxidil for convenience, which may have caused the shedding.
The conversation discusses choosing between titanium fixed needles and a pen with disposable needles for hair loss treatment at a 1.5mm depth. The preference is for disposable needles for better sanitization.
A user tried microneedling for hair loss with a Dr. Pen at 0.8 mm and experienced bleeding, questioning if the intensity was too much. Others suggested a less aggressive approach, and one mentioned finasteride as a helpful treatment without side effects.
Hair loss treatment with latanoprost, minoxidil, and biotin showed progress. Latanoprost, a glaucoma drug, stimulates anagen phase and increases conversion of vellus hair to terminal hair.
The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.
A 23-year-old male shares his positive progress using 0.5mg finasteride for hair loss, noting initial side effects like sore nipples that resolved after adjusting the dosage. Other users discuss their experiences with finasteride, including effects on libido and the trade-offs of using the medication.
The user shared progress pictures showing hair improvement after using topical finasteride and minoxidil since October 2024. The photos were taken in June 2025.
Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.
The conversation discusses hair loss treatments, specifically topical finasteride and minoxidil, with users debating the effectiveness and honesty of progress pictures. Some users claim significant regrowth, while others argue about the influence of lighting and angles on perceived results.
Switching from topical to an oral combo pill (1.2 mg finasteride, 3 mg minoxidil, vitamins) improved hair thickness without noticeable side effects. The user appreciates the convenience of a single daily pill over twice-daily topical applications.
The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.
The conversation is about a 29-year-old man's progress with hair loss treatment over a year using oral finasteride, topical minoxidil, and dermarolling, which has led to improved hair coverage and increased confidence. Users are encouraging and asking about the timeline of noticeable improvements.
A user shared progress pictures after 50 days of using a compound with 10% minoxidil, 0.1% finasteride, and biotin, expressing satisfaction with the results. Another user commented positively on the progress.
A 27-year-old has seen hair regrowth over 5 months using 2ml of 5% minoxidil daily, 50mg of RU58841 daily, and occasional microneedling. Commenters think the results are good and ask about microneedling frequency, needle size, and if ketoconazole shampoo is used.