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      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community Hair Loss Inflammation Prevention Stack

      in Research/Science  46 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community Tretinoin 0.025% cream vs gel ?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses the difficulty of applying tretinoin 0.025% cream on the scalp and considers switching to a gel for easier application. It also mentions that a liquid solution, ideally combined with minoxidil, may be more effective for hair treatment.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Are 10% fluridil formulations effective?

      in Treatment  6 upvotes 2 years ago
      The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

      community Has anyone tried CB-01-03 aka Clascoterone?

      in Research/Science  2 upvotes 3 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Topical Dutasteride 0.025% 2ml once a week

      in Treatment  9 upvotes 1 year ago
      A user discusses using topical dutasteride 0.025% once a week for hair maintenance, alongside fortified minoxidil, RU58841, and Reviv Hair Serum. They seek feedback on the effectiveness of this regimen.

      community Progress since March 21st, 2023

      in Progress Pictures  64 upvotes 2 years ago
      The conversation discusses hair loss treatment progress using 1mg oral finasteride, 10% minoxidil, biotin 0.2%, and LATANO 0.005%. One user reports improved confidence, while another mentions increased libido and a history of depression.

      community The solution for Topical Fin non responders?

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      The user is considering using tretinoin with topical finasteride due to poor absorption and side effects from oral finasteride. They are also contemplating switching to topical dutasteride, while others suggest trying oral minoxidil or lower oral doses.

      community Mix topical finasteride with alfatradiol

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.

      community The mystery of Azelaic Acid

       4 upvotes 11 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community 2 months on topical 5% min+ 0.1% fin

      in Progress Pictures  377 upvotes 2 years ago
      A user shared their progress after using a topical treatment combining 5% Minoxidil and 0.1% Finasteride for two months to address hair loss at the temples. They apply 5ml nightly without side effects and plan to switch to a different brand soon.

      community Topical spironolactone — how many ml do you apply?

      in Female  5 upvotes 1 year ago
      The conversation discusses the use of topical spironolactone for hair loss, with the original poster applying 8 ml daily but learning that 2 ml is recommended. It also touches on hair transplants and the role of DHT sensitivity in hair loss, emphasizing individual differences in treatment outcomes.

      community Spiro for AGA in Europe

       5 upvotes 6 years ago
      Treatment options for female alopecia androgenetica, discussing the availability of spironolactone online in The Netherlands and other potential treatments like finasteride, minoxidil and RU58841.

      community [29 M] 7 month pyrilutamide update.

      in Progress Pictures  126 upvotes 1 year ago
      A 29-year-old male experienced hair regrowth using minoxidil 5% foam and KX826 after stopping finasteride due to side effects. He applies both treatments once daily and reports no side effects from the current regimen.

      community Success: My Doc prescribed me 0.1% Alfatradiol

      in Treatment  13 upvotes 1 year ago
      A user shared their success in getting a prescription for 0.1% Alfatradiol, a topical treatment for hair loss similar to finasteride but with fewer side effects. They found a pharmacy to compound it and will update on the results.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 4 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Topical Fin 0.1% 5% min 7 months review

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      Using topical finasteride 0.1%, minoxidil 5%, and melatonin for 7 months reduced hair loss significantly, with increased libido and decreased stress tolerance. The user applies the solution once daily, uses nizoral twice weekly, and takes vitamin D and ZMA supplements.

      community Topical Min Progress Oct 2024 - Feb 2025

      in Progress Pictures  276 upvotes 1 year ago
      The user experienced hair growth using 5% topical Minoxidil foam twice daily from October 2024 to February 2025, without using finasteride due to family history of side effects. The user is considering other treatments like topical finasteride and received positive feedback on their progress.