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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Pyrilutamide (KX-826) progress?

      in Is this regrowth?  19 upvotes 1 year ago
      The user has been using pyrilutamide 0.5% for over 7 weeks, alongside dutasteride, and noticed some hair improvement, particularly at the temples. They plan to continue and possibly try a 1% solution, with no shedding or side effects reported.

      community At what dose did Spironolactone really start working?

      in Female  2 upvotes 2 years ago
      A user is asking women with androgenic alopecia about the effective dose of spironolactone for hair regrowth, mentioning they've been on 100 mg for a year with minimal results and considering increasing the dose. The conversation focuses on the effectiveness of spironolactone for hair loss treatment.

      community Topical ( Fin+Min+Arginine) wow?

      in Progress Pictures  10 upvotes 2 years ago
      The conversation is about hair loss treatment using topical minoxidil, finasteride, and arginine, showing noticeable progress in one month. The user suggests adding arginine serum for better results.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community Finally got hold of 0.1% latanoprost

      in Treatment  7 upvotes 3 months ago
      The conversation is about a user obtaining a compounded treatment for hair loss, including 0.1% latanoprost, 0.2% melatonin, and 1% cetirizine. The user also uses 2.5 mg dutasteride, 5 mg minoxidil, and RU58841 daily, and is at Norwood 2.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 9 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community How effective is topical spironolactone for androgenic alopecia?

      in Female  1 upvotes 1 year ago
      Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.

      community 6 weeks minoxidil… and spironolactone

      in Progress Pictures  34 upvotes 8 months ago
      Minoxidil and spironolactone are used for hair regrowth, with visible progress noted. Spironolactone is discussed as a treatment option, particularly in the context of transitioning, with concerns about its effects on men.

      community Those with Success with RU58841: Where do you buy it?

      in Treatment  13 upvotes 3 years ago
      The conversation is about where to buy RU58841 for hair loss treatment and tips for its use, with one user suggesting buying powder from a lab in China to save money and sharing their positive 11-week results.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 3 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community My Pyrilutamide Experience so far

      in Update  78 upvotes 3 years ago
      A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

      community Progress finally (?) 4 months left & right temple

      in Is this regrowth?  38 upvotes 3 months ago
      The user has been using finasteride for two years without results and recently started a new routine involving derma stamping, retinol, and minoxidil, which seems to show progress. The user microneedles about half the week and uses L’Oréal night serum for retinol.

      community Pyrilutamide kintor pharmaceutical

      in Chat  6 upvotes 2 years ago
      The conversation is about seeking information on GT20029 from Kintor Pharmaceutical as a potential hair loss cure and inquiring about experiences with CosmeaRNA.

      community Earliest we can get legitimate pyrilutamide

      in Research/Science  48 upvotes 4 years ago
      Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

      community Do any shampoos contain Piroctone Olamine in the US

      in Product  3 upvotes 1 year ago
      The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  14 upvotes 3 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Is regrowth normally painfully slow?

      in Treatment  5 upvotes 1 year ago
      The user is experiencing slow but solid hair regrowth using topical finasteride, oral minoxidil, keto shampoo, microneedling, RU58841, and rosemary oil. Another user suggests being grateful for the dense coverage.

      community Anyone had any success with PRP?

      in Treatment  1 upvotes 2 years ago
      The user experienced eyebrow hair loss after COVID-19 and has not seen regrowth despite using Latisse. They are seeking new treatment options but are cautious about spending money on ineffective solutions.

      community Fellas, is Arteta world class hair density?

      in Satire  361 upvotes 2 years ago
      The conversation is about the impressive hair density and hairline of a person, with users attributing it to good genetics and joking about the lack of hair loss despite stress. Specific hair loss treatments like Minoxidil, Finasteride, or RU58841 are not discussed.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  4 upvotes 1 year ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.
      Norwood scale ? 28m

      community Norwood scale ? 28m

      in General  68 upvotes 1 year ago
      A 28-year-old is assessing their hair loss on the Norwood scale, considering adding topical minoxidil and dermastamping to their current regimen of oral finasteride and minoxidil. They feel their hair loss is worsening and seek opinions on their condition.