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      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 1 year ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 1 year ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community Regimen proposal (incl. dut meso) (event industry)

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       23 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

      community What has your 0.5mg/daily dutasteride timeline been?

      in Research/Science  34 upvotes 1 year ago
      Many users report switching from finasteride to dutasteride with mixed results, often experiencing increased shedding and minimal regrowth. Some users find dutasteride more effective in slowing hair loss, while others see no improvement or even regression.

      community Dut, 0.5mg once a day and never stop

      in Progress Pictures  427 upvotes 4 weeks ago
      The conversation discusses the use of dutasteride (0.5 mg daily) for hair loss, with additional treatments like minoxidil, derma rolling, and nizoral shampoo. The user reports positive progress over two years with no significant side effects, emphasizing the importance of consistency and patience.

      community RU/Pyrilutamide access and purchase

      in Product  3 upvotes 3 months ago
      The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

      community European release of clascoterone

      in Research/Science  12 upvotes 1 week ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 11 months ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community 6 weeks 5mg min 0.5mg dut progress

      in Progress Pictures  7 upvotes 1 year ago
      A 35-year-old man shares his positive progress in hair regrowth using a daily routine of 5mg oral minoxidil and 0.5mg dutasteride, along with a low light cap, weekly dermarolling, and biweekly ketoconazole shampoo. He reports noticeable improvements without side effects and aims to inspire others considering similar treatments.

      community M25 Dutasteride is the best thing that ever happened to me

      in Update  90 upvotes 1 month ago
      A 25-year-old switched from finasteride to dutasteride, experiencing significant hair regrowth and improved hair quality after 6 months, taking it three times a week. The user stopped finasteride entirely, citing dutasteride's longer half-life as more effective.
      37 days on dut 0.5mg at 17 progress

      community 37 days on dut 0.5mg at 17 progress

      in General  23 upvotes 1 year ago
      A user shared progress photos after 37 days of using 0.5mg dutasteride for hair loss at age 17. The discussion focuses on the effectiveness of this treatment.

      community Confused re RU58841 checkout options

      in Finasteride/Dutasteride 1 year ago
      The conversation is about using RU58841 for hair loss, discussing the stability of the powder form and the need for a carrier solution like KB or PG + ethanol. The user is advised to mix RU58841 with stemoxydine and store it properly, while also considering safety precautions.

      community 50% test increase after 18 months of taking DUT

      in Update  57 upvotes 1 year ago
      A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.