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      community Been on Dut for 2 1/2 years. AMA

      in Finasteride/Dutasteride  20 upvotes 4 months ago
      The user shares a positive experience with Dutasteride for hair loss, noting increased hair density and minimal side effects after switching from Finasteride. They prefer oral Dutasteride and avoid Minoxidil due to its inconvenience and potential risks.
      29M, Noticing More Scalp Visibility After 3 Years of Hair Shedding

      community 29M, Noticing More Scalp Visibility After 3 Years of Hair Shedding

      in General  68 upvotes 4 months ago
      The user noticed increased hair loss over the past three years and is seeking advice. A suggestion was made to consult a dermatologist or trichologist and consider blood tests, particularly for vitamin D levels, to address potential androgenetic alopecia (AGA).

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 5 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Serum based on plant extracts boosts hair growth in weeks.

      in Treatment  44 upvotes 6 months ago
      A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 6 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community Should I risk changing to Dutasteride?

      in Finasteride/Dutasteride  10 upvotes 7 months ago
      The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.

      community New Study: PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hair follicle stem cells and stimulate natural hair growth by 20%

      in Research/Science  839 upvotes 7 months ago
      PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hair follicle stem cells and increase hair growth by 20% in eight weeks, unlike minoxidil or finasteride. However, skepticism remains about its effectiveness and availability, with concerns about funding and the timeline for broader access.

      community 1.5 years on min+fin topical solution still hair falls like crazy

      in Progress Pictures  54 upvotes 8 months ago
      The user has been using a minoxidil and finasteride topical solution for 1.5 years without improvement and recently added oral finasteride but still experiences significant hair shedding. Other users suggest trying dutasteride, as some have switched from finasteride to dutasteride with fewer side effects, while others discuss dosage strategies and the effectiveness of topical versus oral treatments.

      community Losing hairs is not the same as balding

      in Chat  151 upvotes 8 months ago
      Hair loss treatments like finasteride, dutasteride, and minoxidil can cause initial shedding as they restart the hair growth cycle, but this is not an indicator of treatment failure. The effectiveness of these treatments should be judged by cosmetic changes over time, not by daily hair loss counts.

      community If you cannot tolerate fin, are natural oil even worth it

      in Product  8 upvotes 8 months ago
      Minoxidil and finasteride are effective for hair loss, but natural oils like pumpkin seed oil and saw palmetto are not proven to be effective. Topical finasteride may be an option for those who cannot tolerate oral finasteride.

      community Flakey scalp due to minoxidil?

      in Minoxidil  7 upvotes 9 months ago
      Minoxidil can cause scalp flaking and dryness, often due to its alcohol content. Switching to foam minoxidil or using antifungal shampoos like Ketoconazole may help reduce these side effects.

      community The DEFINITIVE cure for hairloss

      in Satire  270 upvotes 10 months ago
      The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

      community What I would tell my younger self when I started losing hair

      in Chat  197 upvotes 10 months ago
      Hair loss is emotionally challenging, but acceptance and focusing on other life aspects are important. Treatments like finasteride, minoxidil, and RU58841 are discussed, with emphasis on the emotional impact over physical changes.

      community The (many) benefits of buzzing during treatment

      in Chat  28 upvotes 10 months ago
      Buzzing hair can improve mental health and make applying treatments like Minoxidil and microneedling easier. It helps with self-acceptance and reduces the impact of hair loss on appearance.

      community Let’s talk about micro needling

      in Microneedling  14 upvotes 10 months ago
      Microneedling combined with minoxidil is more effective for hair growth than microneedling alone. Optimal results are seen with weekly microneedling using 0.5 - 1mm needles and regular minoxidil application, avoiding minoxidil on the needled area for 24 hours.

      community Taking creatine while being on Fin

      in Finasteride/Dutasteride  5 upvotes 10 months ago
      Creatine does not cause hair loss, but it may accelerate hair loss in those predisposed to male pattern baldness. Finasteride users report mixed experiences with creatine, with some noticing no change and others experiencing increased shedding.

      community About those dutasteride studies πŸ˜’

      in Research/Science  21 upvotes 11 months ago
      Dutasteride studies for hair loss are often sponsored by GlaxoSmithKline, raising concerns about potential bias. Despite this, some users report positive results with dutasteride and oral minoxidil, while others remain skeptical of industry-funded research.

      community Is this Better Than Topical Minoxidil? Topical Diazoxide

      in Research/Science  4 upvotes 11 months ago
      Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

      community New molecule PP405 vs exercise

      in Research/Science  36 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Are Derma Rollers Actually Harmful in the Long Run?

      in Microneedling  40 upvotes 1 year ago
      Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

      community Inflammation (and health care system) frustration

      in Female  6 upvotes 1 year ago
      A woman is frustrated with her hair loss and the slow, ineffective healthcare system in Canada. She has tried treatments like minoxidil, doxycycline, and kenalog injections, but continues to experience painful inflammation and hair loss.