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GlossaryLeukocytosis

condition with elevated white blood cell count

Leukocytosis is a condition characterized by an elevated number of white blood cells (leukocytes) in the bloodstream. This increase often indicates an immune response to infections, inflammation, stress, or other medical conditions such as leukemia. For a professional, it is important to identify the underlying cause of leukocytosis to determine the appropriate treatment or intervention.

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community Bloodwork after 8 months on finasteride, is this normal?

in Update 27 upvotes 2 years ago

A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

community Help me interpret my bloods

in General 65 upvotes 1 year ago

The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

in Treatment 11 upvotes 5 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 30 upvotes 4 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community telogen effluvium hair loss. Has anyone had it and could tell me anything about it?

in Treatment 1 upvotes 6 years ago

The user experienced hair thinning from chromium and alpha lipoic acid supplements, which stopped after discontinuing them. Someone mentioned this could be telogen effluvium, a temporary condition.

community blood DHT levels shot up after doubling dutasteride dosage

in Finasteride/Dutasteride 20 upvotes 2 years ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 2 years ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community Follicum releases some data from previous phase 2a trial

in Research/Science 14 upvotes 3 years ago

Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

community Thoughts on Lactobacillus Reuteri 6475?

in Treatment 3 upvotes 1 year ago

Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

community Lysine IS helping

in Update 4 upvotes 5 years ago

Lysine supplementation at 2 grams daily reduced hair shedding by 25% and made hair strands thicker. The user highly recommends lysine for hair health.

community Anagenic is trying to compound Gt20029

in Treatment 56 upvotes 3 years ago

The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

community A less common type of hairloss case

in Research/Science 4 upvotes 1 month ago

High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

community Blood Results (UPDATED) TOTAL T 1279 ng/dL- 2 Yrs on Fin / 1.5 Yrs on Dut

in Finasteride/Dutasteride 9 upvotes 10 months ago

The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.

community Clascoterone (Winlevi) now approved in Canada

in Product 14 upvotes 2 years ago

The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

community AA and Hirsutism but T levels are normal

in Female 5 upvotes 5 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community Finasteride with high estradiol levels

in Finasteride/Dutasteride 6 upvotes 2 years ago

A 22-year-old with high estradiol levels is considering starting finasteride for hair loss. They have an upcoming endocrinologist appointment to discuss whether they should proceed with the treatment.

community Clascoterone (Winlevi) Update for Canada

in Treatment 15 upvotes 3 years ago

Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

community Shedding on pyri (KX-826) is this normal?

in Update 9 upvotes 1 year ago

A user experienced increased shedding after adding KX-826 to their long-term finasteride and minoxidil regimen. Another user reported mild side effects from KX-826, such as stomach and testicle pain.

community PP405 - hair stem cell stimulation

in Research/Science 53 upvotes 2 years ago

PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

community Am I crazy or is this recovery?

in Is this regrowth? 134 upvotes 1 year ago

The user is experiencing sudden hair loss and is considering micro-needling, low-level light therapy, iron supplements, folihair, and Omega 3. They are hesitant to start finasteride, suspecting the hair loss might be due to telogen effluvium from a past COVID-19 infection.

community Winlevi (clascoterone 1%) anyone trying it

in Treatment 2 upvotes 5 months ago

Winlevi (clascoterone 1%) is being discussed as a potential hair loss treatment. Users are considering its use despite concerns about its delivery method.

community Bloodwork before/after starting Finasteride (5 months)

in Finasteride/Dutasteride 1 upvotes 1 year ago

A user reported a significant increase in testosterone and estradiol levels after taking Finasteride for 5 months, with estradiol levels rising over 2000%. They plan to consult their doctor, suspecting a lab error, as they feel fine with no side effects.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 22 upvotes 2 years ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community Blood work after 4 month topical fin/min

in Update 6 upvotes 1 year ago

After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

community EMA is re-examining Winlevi (clascoterone at lower concentration)

in Treatment 8 upvotes 11 months ago

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

community Massive Telofen Effluvium after months sick. I already had enough shedding due to Seborrheic Dermatitis. I don’t know where to start.

in General 96 upvotes 1 year ago

The conversation is about dealing with hair shedding due to seborrheic dermatitis and recent illness. Recommendations include treating seborrheic dermatitis with ketoconazole, correcting vitamin D deficiency, and improving sleep.

community CTE and lots of shedding for over a year

in Female 5 upvotes 2 years ago

A female user has experienced severe hair shedding since stopping birth control in late 2022, diagnosed as telogen effluvium with no signs of androgenetic alopecia. Despite healthy living and optimal bloodwork, she continues to shed hair daily but also sees significant regrowth.

community Bloodwork Results. DHT and Testosterone Levels

in Update 6 upvotes 2 years ago

The user shared their bloodwork results showing DHT at 17 ng/dl and testosterone at 287 ng/dl, with a slight Vitamin D deficiency. They are seeking opinions on these levels and have an upcoming dermatologist appointment.

community 2,5-3 months progress. I might be a hyper responder?

in Is this regrowth? 17 upvotes 2 months ago

The user is experiencing reduced hair shedding and increased hair density after using finasteride, minoxidil, derma rolling, granactive retinoid, and Nizoral, while also taking testosterone and aromatase inhibitors. They question if they are a hyper responder to the treatments, despite mixed feedback from others about visible progress.

community What’s wrong with my scalp?

in General 59 upvotes 1 year ago

The user is experiencing white flakes on their scalp despite using anti-dandruff shampoos and oils for six weeks. A suggestion was made to try ketoconazole at higher concentrations, as it might be seborrheic dermatitis, which can lead to hair loss if untreated.