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      community Pyrilutamide isn’t failed at all.

      in Technology  11 upvotes 1 year ago
      Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Best thing you can do for your hair, MCT Oil

      in Treatment  1 upvotes 3 weeks ago
      MCT oil helps reduce dandruff, flaking, and itching, and may slow hair loss progression. Eliminating sugar and dairy also stabilizes hair loss, while zinc, sugar, and dairy can worsen scalp conditions.

      community Where to get liposomal finasteride?

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      The conversation discusses finding a reliable source for liposomal finasteride. The user currently uses a topical product with Minoxidil, finasteride, retinoic acid, and hydrocortisone, and is considering MinoxidilMax's Maxogen-x.

      community What blood test to do before starting fin?

      in Finasteride/Dutasteride  1 upvotes 3 months ago
      A user is considering starting finasteride for hair thinning but is concerned about side effects like low libido and gynecomastia. They plan to consult a dermatologist and are advised to test DHT, testosterone, and estradiol levels.

      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 3 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 1 year ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community How strong is topical spiro? Close to God tier stack.

      in Product  8 upvotes 3 years ago
      Topical spiro's effectiveness on androgens is discussed. User tried oral DUT, oral Min, keto/nizoral, and RU but experienced worsening hair loss and chest pains. Suggestion given to increase dutasteride and oral minoxidil dosage before considering spironolactone.

      community how to make dut pills from dut powder

      in Research/Science 4 months ago
      A user discusses making DIY dutasteride capsules from powder bought from China, using a mix of MCT oil and propylene glycol. Others warn about the risks of incorrect dosing, potential degradation, and the possibility of receiving fake products.

      community Mixing tretinoin/finasteride with minoxidil?

      in Treatment  1 upvotes 1 year ago
      Combining finasteride with minoxidil and tretinoin is discussed, with concerns about potential overdose. It is suggested that high doses of finasteride do not provide additional benefits beyond 1 mg.

      community UPDATE - 7 months 2,5 dutatesteride

      in Update  9 upvotes 1 year ago
      The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2446 upvotes 5 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community I use the big 4 to combat but I need to do more

      in Minoxidil  3 upvotes 8 months ago
      The conversation discusses various hair loss treatments, including Minoxidil, Finasteride, Dutasteride, Ketoconazole shampoo, microneedling, and supplements like collagen, biotin, and vitamins. Users suggest additional treatments like red light therapy, scalp massages, and possibly adding RU58841 or Tretinoin.

      community Fluridil/topilutamide experince

      in Treatment  5 upvotes 2 years ago
      A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.

      community 4 months on finasteride and minoxidil

      in Progress Pictures  193 upvotes 3 months ago
      A 19-year-old is using 5% topical minoxidil and 1mg oral finasteride daily for hair growth, showing progress after 4 months. Users suggest adding ketoconazole shampoo to address scalp inflammation and dandruff.

      community March 21st vs July 9th! Topical fin, minox, latanoprost, and biotin

      in Progress Pictures  118 upvotes 2 years ago
      The user "cooler1082" shared their progress pictures for hair loss after using topical finasteride, minoxidil, latanoprost, and biotin. Other users commented on the positive results and asked about the specific dosages used. One user mentioned that latanoprost is an eye medication that has shown some potential for treating hair loss.

      community Ben Greenfield Podcast : CHK-Cu & C-60

      in Research/Science  5 upvotes 4 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.