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      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  56 upvotes 1 year ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 3 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       23 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

      community PSA: Greasy, product laden hair makes the scalp 10x more visible

      in Treatment  30 upvotes 1 year ago
      Greasy or product-laden hair can make the scalp appear more visible, leading some to mistakenly think they are balding. Proper hair washing and avoiding heavy products can help assess true hair thickness, and treatments like finasteride are used by some for actual hair loss.

      community Pyrilutamide: hairloss continues

      in Treatment  12 upvotes 3 years ago
      The conversation is about someone experiencing continued hair loss despite using Pyrilutamide and considering the need for more time or better quality control for the treatment. Another person suggests waiting for the drug to be officially approved due to potential quality issues with current products.

      community Is the clinic diagnosis legit to you ?

      in Transplants  1 upvotes 1 year ago
      The clinic diagnosed the user with NW3 and AGA, noting thinning hair despite using finasteride for 3 years, and suggested PRP and Mesotherapy before considering a transplant. The user questions the necessity of these treatments without confirming retrograde alopecia and its treatability.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  19 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Finasteride vs RU58841 vs Dutasteride for MPB, Diffuse Thinning, or Retrograde Alopecia

      in Minoxidil  6 upvotes 1 year ago
      The user is seeking advice on the best treatment for male pattern baldness, diffuse thinning, and retrograde alopecia, comparing the effectiveness of finasteride, RU58841, and dutasteride, and considering whether to add minoxidil or switch to dutasteride or combine treatments. They are currently on finasteride and are contemplating if adding RU58841 or switching to dutasteride is better, and also asking about the comparison between pyrilutamide and RU58841.

      community Expectations control for SCUBE3

      in Research/Science  20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Questions about DUPA and figuring out what my hairloss is (NEED INPUT BADLY)

      in Finasteride/Dutasteride  5 upvotes 11 months ago
      The conversation discusses severe hair shedding and thinning, with the original poster using finasteride, oral minoxidil, and other supplements without improvement. The discussion highlights the possibility of telogen effluvium and the importance of addressing potential underlying health issues, such as stress and gut health, rather than assuming diffuse unpatterned alopecia (DUPA).

      community Hair Loss "a matter of survival" in South Korea

      in Research/Science  335 upvotes 3 months ago
      South Korea's president is advocating for hereditary hair loss to be covered by national health insurance due to its impact on mental health and daily functioning. The discussion highlights the societal pressure in South Korea regarding appearance and the potential benefits of treating hair loss to improve mental health.

      community B12 deficiency hairloss (hair thinning)

      in Treatment  7 upvotes 7 months ago
      Hair loss due to vitamin B12 deficiency is discussed, with some users suggesting supplements and dietary changes, while others recommend medications like finasteride or dutasteride. The conversation highlights differing opinions on the cause of hair loss, with some attributing it to genetics or male pattern baldness.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community A Different Take on Curing MBP

       15 upvotes 7 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

      community 5+ years on meds, still losing

      in Progress Pictures 6 months ago
      The user has been on finasteride and minoxidil since 2020 and increased dutasteride and minoxidil doses in June 2024, but still experiences hair loss. Despite trying pyrilutamide without success, opinions vary on whether the hair loss is significant, with some suggesting it might be due to lighting, angles, or a regular shedding cycle.